Substituted piperazines are a class of chemical compounds based on a piperazine core.[1] Some are used as recreational drugs and some are used in scientific research.[2]
^Laras, Y.; Garino, C.; Dessolin, J.; Weck, C.; Moret, V.; Rolland, A.; Kraus, J.-L. (2009-02-01). "New N4-substituted piperazine naphthamide derivatives as BACE-1 inhibitors". Journal of Enzyme Inhibition and Medicinal Chemistry. 24 (1): 181–187. doi:10.1080/14756360802048939. ISSN 1475-6366. PMID 18770069. S2CID 85385527.
^Alghamdi, Saad; Alshehri, Mohammed M.; Asif, Mohammad (2022). "The Neuropharmacological Potential of Piperazine Derivatives: A Mini- Review". Mini-Reviews in Organic Chemistry. 19 (7): 798–810. doi:10.2174/1570193x19666220119120211.
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Substitutedpiperazines are a class of chemical compounds based on a piperazine core. Some are used as recreational drugs and some are used in scientific...
Piperazine (/paɪˈpɛrəziːn/) is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring...
recreational drug of the phenylpiperazine chemical class and is a substitutedpiperazine. Usually in combination with benzylpiperazine (BZP) and other analogues...
to predate their interest in piperazines as antihelminthics. Even so, the majority of the early work with the piperazines were investigations into their...
ways (i) by substitution at the second nitrogen atom of the piperazine ring with alkyl, benzyl, haloalkyl or phenyl groups; (ii) by substitution in the aromatic...
mediated predominantly or fully by blockade of the 5-HT2C receptor. Substitutedpiperazine Diphenylpiperazine Phenylpiperazine Quipazine Schoeffter P, Hoyer...
4-Substituted-2,5-dimethoxyamphetamines (DOx) is a chemical class of substituted amphetamine derivatives featuring methoxy groups at the 2- and 5- positions...
similarly an antagonist. A major metabolite of buspirone, 1-(2-pyrimidinyl)piperazine (1-PP), occurs at higher circulating levels than buspirone itself and...
(4) displaces one of the piperonyl groups to give fipexide (5). Substitutedpiperazine Befuraline Piberaline Missale C, Pasinetti G, Govoni S, Spano PF...
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