In food safety, the concept of substantial equivalence holds that the safety of a new food, particularly one that has been genetically modified (GM), may be assessed by comparing it with a similar traditional food that has proven safe in normal use over time.[1] It was first formulated as a food safety policy in 1993, by the Organisation for Economic Co-operation and Development (OECD).[2]
As part of a food safety testing process, substantial equivalence is the initial step, establishing toxicological and nutritional differences in the new food compared to a conventional counterpart—differences are analyzed and evaluated, and further testing may be conducted, leading to a final safety assessment.[3]
Substantial equivalence is the underlying principle in GM food safety assessment for a number of national and international agencies, including the Canadian Food Inspection Agency (CFIA), Japan's Ministry of Health, Labour and Welfare (MHLW), the US Food and Drug Administration (FDA), and the United Nations' Food and Agriculture Organization (FAO) and World Health Organization.[4]
^Safety Evaluation of Foods Derived by Modern Biotechnology: Concepts and Principles OECD (1993)
^Schauzu, Marianna (Apr 2000). "The concept of substantial equivalence in safety assessment of foods derived from genetically modified organisms" (PDF). AgBiotechNet. 2.
^Cite error: The named reference kok was invoked but never defined (see the help page).
^"Substantial Equivalence in Food Safety Assessment" (PDF). Council for Biotechnology Information. March 2001. Archived (PDF) from the original on 7 February 2016. Retrieved 6 February 2016. () (Page archive)
and 27 Related for: Substantial equivalence information
In food safety, the concept of substantialequivalence holds that the safety of a new food, particularly one that has been genetically modified (GM),...
Countries such as the United States, Canada, Lebanon and Egypt use substantialequivalence as the starting point when assessing safety, while many countries...
replace the substantialequivalence standard with safety studies. In a 2016 review, Domingo criticized the use of the "substantialequivalence" concept as...
only looks at verifiable scientific risks and uses the concept of substantialequivalence. The European Union by contrast has possibly the most stringent...
Countries such as the United States, Canada, Lebanon and Egypt use substantialequivalence to determine if further testing is required, while many countries...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
responsible for β-carotene biosynthesis. This variety of rice holds substantial promise for reducing the incidence of vitamin A deficiency in the world's...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
controversial. Cultivation of herbicide-resistant corn in the EU provides substantial farm-level benefits. Bt maize/Bt corn is a variant of maize that has...
traditional crops. Moreover, they believe that the FDA follows the substantialequivalence rule not because of the science, but because the FDA was corrupted...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
in their legally prescribed duty to enforce the requirement of "substantialequivalence" in Hasidic schools, though not naming specific schools of concern...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
Organization, Geneva WHO (1995) Application of the principle of substantialequivalence to the safety evaluation of foods or food components from plants...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
ingredient. Generally recognized as safe and effective Novel food Substantialequivalence "How U.S. FDA's GRAS Notification Program Works (original January...
existed prior to February 15, 2007, applicants can apply via the SubstantialEquivalence (SE) regulatory pathway. On May 10, 2016, the US FDA finalized...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
sources. In each case, these applications have been simplified or substantialequivalence applications, because astaxanthin is recognised as a food component...
Rice Soybean Potato History and regulation History Regulation Substantialequivalence Cartagena Protocol on Biosafety Process Techniques Molecular cloning...
conclude that the data presented in these articles does not provide any substantial evidence of GMO harm. The presented articles suggesting possible harm...
Global Information