Subcortical ischemic depression, also known as vascular depression, is a medical condition most commonly seen in older people with major depressive disorder. Subcortical ischemic depression refers to vascular depression specifically due to lesions and restricted blood flow, known as ischemia, in certain parts of the brain. However, the disorder is typically described as vascular depression in the literature.
There is no formal and accepted definition of vascular depression and the hypothesis requires further research to support the causal link between these vascular lesions and depression.[1] Thus, it is difficult to determine if vascular depression can be considered a distinct sub-type of major depressive disorder (MDD). However, with current criteria, some studies estimate that vascular depression may account for over half of the cases of MDD in the elderly.
^Aizenstein, HJ; Baskys, A; et al. (3 November 2016). "Vascular depression consensus report - a critical update". BMC Medicine (Editorial). 14 (1): 161. doi:10.1186/s12916-016-0720-5. PMC 5093970. PMID 27806704.
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