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Sorangium cellulosum information


Sorangium cellulosum
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Myxococcota
Class: Myxococcia
Order: Myxococcales
Family: Polyangiaceae
Genus: Sorangium
Species:
S. cellulosum
Binomial name
Sorangium cellulosum
(ex Jahn 1924) Reichenbach 2007

Sorangium cellulosum is a soil-dwelling Gram-negative bacterium of the group myxobacteria.[1] It is motile and shows gliding motility. Under stressful conditions this motility, as in other myxobacteria, the cells congregate to form fruiting bodies and differentiate into myxospores. These congregating cells make isolation of pure culture and colony counts on agar medium difficult as the bacterium spread and colonies merge.[2] It has an unusually-large genome of 13,033,779 base pairs, making it the largest bacterial genome sequenced to date by roughly 4 Mb.[3][4]

  1. ^ Julien B, Fehd R (2003). "Development of a mariner-based transposon for use in Sorangium cellulosum". Appl Environ Microbiol. 69 (10): 6299–301. Bibcode:2003ApEnM..69.6299J. doi:10.1128/AEM.69.10.6299-6301.2003. PMC 201241. PMID 14532095.
  2. ^ Reichenbach H.; Hofle, G. (1999). "Myxobacteria as producer of secondary metabolites". In Grabley, S.; Thiericke, R. (eds.). Drug Discovery from Nature. pp. 149–179. ISBN 978-3-540-66947-0.
  3. ^ Schneiker S, et al. (2007). "Complete genome sequence of the myxobacterium Sorangium cellulosum". Nature Biotechnology. 25 (11): 1281–1289. doi:10.1038/nbt1354. PMID 17965706.
  4. ^ "Largest known bacterial genome size - Bacteria Sorangium cellulosum - BNID 104469". bionumbers.hms.harvard.edu. Retrieved 2024-05-02.

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Sorangium cellulosum

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Sorangium cellulosum is a soil-dwelling Gram-negative bacterium of the group myxobacteria. It is motile and shows gliding motility. Under stressful conditions...

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Myxobacteria

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million nucleotides. The second largest is another myxobacteria Sorangium cellulosum. Myxobacteria can move by gliding. They typically travel in swarms...

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Genome

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(November 2007). "Complete genome sequence of the myxobacterium Sorangium cellulosum". Nature Biotechnology. 25 (11): 1281–1289. doi:10.1038/nbt1354....

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Boron

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discovered in the 1990s from culture broth of the myxobacterium Sorangium cellulosum. In 2013, scientist proposed that life on Mars began when boron and...

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Tartrolon

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antibiotics discovered in 1994 from the culture broth of the myxobacterium Sorangium cellulosum. Two variants of tartrolons, A and B, were identified. Tartrolon...

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Chromosome

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to more than 14,000,000 base pairs in the soil-dwelling bacterium Sorangium cellulosum. Spirochaetes of the genus Borrelia are a notable exception to this...

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Secondary metabolite

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Epothilones, macrolactones from the soil-dwelling myxobacterium Sorangium cellulosum. Erythromycin, Saccharopolyspora erythraea. Nystatin, from Streptomyces...

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Utidelone

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which are metabolites produced by the soil-dwelling myxobacterium Sorangium cellulosum. It is also known as epothilone D. "New Drug Approvals in China in...

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Chlorotonil A

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A is a polyketide natural product produced by the myxobacterium Sorangium cellulosum So ce1525. It displays antimalarial activity in an animal model,...

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Bacteria

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to 12,200,000 base pairs (12.2 Mbp) in the soil-dwelling bacteria Sorangium cellulosum. There are many exceptions to this; for example, some Streptomyces...

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Disorazol

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Disorazol, a cyclic polyketide synthesized by the bacterium Sorangium cellulosum So ce12, was first detected and isolated in 1994. Its chemical structure...

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Epothilone

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identified as metabolites produced by the soil-dwelling myxobacterium Sorangium cellulosum. As of September 2008[update], epothilones A to F have been identified...

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Pxr sRNA

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aurantiaca. Homologs were not found in any other myxobacteria (such as Sorangium cellulosum or Anaeromyxobacter dehalogenans) which suggests the Pxr RNA gene...

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Bacterial genome

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W; Wu, ZH; Qin, N; Li, YZ (2013). "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline milieu". Scientific Reports. 3: 2101. Bibcode:2013NatSR...

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CYP109 family

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Bernhardt, R (January 2013). "Novel family members of CYP109 from Sorangium cellulosum So ce56 exhibit characteristic biochemical and biophysical properties"...

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Myxococcus xanthus

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competition and communication with the ambruticin-producing myxobacterium Sorangium cellulosum. It has been shown that an M. xanthus swarm is capable of eavesdropping...

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Gladiolin

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a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum". Journal of the American Chemical Society. 130 (43): 14234–14243...

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Mitotic inhibitor

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cancer. Epothilones are derived from a fermenting soil bacteria, Sorangium cellulosum and it was found to be too toxic for use as an antifungal. Epothilones...

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List of sequenced bacterial genomes

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Schneiker; et al. (2007). "Complete genome sequence of the myxobacterium Sorangium cellulosum". Nature Biotechnology. 25 (11): 1281–1289. doi:10.1038/nbt1354....

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Ixabepilone

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analog of epothilone B, a natural chemical compound produced by Sorangium cellulosum. Epothilone B itself could not be developed as a pharmaceutical drug...

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Boromycin

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acylation position. Experiments with feeding the production strain Sorangium cellulosum with specific isotopes have shed light on the biosynthesis of tartrolons...

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