Sorangium cellulosum is a soil-dwelling Gram-negative bacterium of the group myxobacteria.[1] It is motile and shows gliding motility. Under stressful conditions this motility, as in other myxobacteria, the cells congregate to form fruiting bodies and differentiate into myxospores. These congregating cells make isolation of pure culture and colony counts on agar medium difficult as the bacterium spread and colonies merge.[2] It has an unusually-large genome of 13,033,779 base pairs, making it the largest bacterial genome sequenced to date by roughly 4 Mb.[3][4]
^Julien B, Fehd R (2003). "Development of a mariner-based transposon for use in Sorangium cellulosum". Appl Environ Microbiol. 69 (10): 6299–301. Bibcode:2003ApEnM..69.6299J. doi:10.1128/AEM.69.10.6299-6301.2003. PMC 201241. PMID 14532095.
^Reichenbach H.; Hofle, G. (1999). "Myxobacteria as producer of secondary metabolites". In Grabley, S.; Thiericke, R. (eds.). Drug Discovery from Nature. pp. 149–179. ISBN 978-3-540-66947-0.
^Schneiker S, et al. (2007). "Complete genome sequence of the myxobacterium Sorangium cellulosum". Nature Biotechnology. 25 (11): 1281–1289. doi:10.1038/nbt1354. PMID 17965706.
Sorangiumcellulosum is a soil-dwelling Gram-negative bacterium of the group myxobacteria. It is motile and shows gliding motility. Under stressful conditions...
million nucleotides. The second largest is another myxobacteria Sorangiumcellulosum. Myxobacteria can move by gliding. They typically travel in swarms...
discovered in the 1990s from culture broth of the myxobacterium Sorangiumcellulosum. In 2013, scientist proposed that life on Mars began when boron and...
antibiotics discovered in 1994 from the culture broth of the myxobacterium Sorangiumcellulosum. Two variants of tartrolons, A and B, were identified. Tartrolon...
to more than 14,000,000 base pairs in the soil-dwelling bacterium Sorangiumcellulosum. Spirochaetes of the genus Borrelia are a notable exception to this...
Epothilones, macrolactones from the soil-dwelling myxobacterium Sorangiumcellulosum. Erythromycin, Saccharopolyspora erythraea. Nystatin, from Streptomyces...
which are metabolites produced by the soil-dwelling myxobacterium Sorangiumcellulosum. It is also known as epothilone D. "New Drug Approvals in China in...
A is a polyketide natural product produced by the myxobacterium Sorangiumcellulosum So ce1525. It displays antimalarial activity in an animal model,...
to 12,200,000 base pairs (12.2 Mbp) in the soil-dwelling bacteria Sorangiumcellulosum. There are many exceptions to this; for example, some Streptomyces...
Disorazol, a cyclic polyketide synthesized by the bacterium Sorangiumcellulosum So ce12, was first detected and isolated in 1994. Its chemical structure...
identified as metabolites produced by the soil-dwelling myxobacterium Sorangiumcellulosum. As of September 2008[update], epothilones A to F have been identified...
aurantiaca. Homologs were not found in any other myxobacteria (such as Sorangiumcellulosum or Anaeromyxobacter dehalogenans) which suggests the Pxr RNA gene...
W; Wu, ZH; Qin, N; Li, YZ (2013). "Extraordinary expansion of a Sorangiumcellulosum genome from an alkaline milieu". Scientific Reports. 3: 2101. Bibcode:2013NatSR...
Bernhardt, R (January 2013). "Novel family members of CYP109 from Sorangiumcellulosum So ce56 exhibit characteristic biochemical and biophysical properties"...
competition and communication with the ambruticin-producing myxobacterium Sorangiumcellulosum. It has been shown that an M. xanthus swarm is capable of eavesdropping...
a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangiumcellulosum". Journal of the American Chemical Society. 130 (43): 14234–14243...
cancer. Epothilones are derived from a fermenting soil bacteria, Sorangiumcellulosum and it was found to be too toxic for use as an antifungal. Epothilones...
analog of epothilone B, a natural chemical compound produced by Sorangiumcellulosum. Epothilone B itself could not be developed as a pharmaceutical drug...
acylation position. Experiments with feeding the production strain Sorangiumcellulosum with specific isotopes have shed light on the biosynthesis of tartrolons...