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Skimmianine information


Skimmianine
Names
Preferred IUPAC name
4,7,8-Trimethoxyfuro[2,3-b]quinoline
Other names
Skimmianin; β-Fagarine; Chloroxylonine
Identifiers
CAS Number
  • 83-95-4 checkY
3D model (JSmol)
  • Interactive image
PubChem CID
  • 6760
UNII
  • 4E1KLC380B checkY
CompTox Dashboard (EPA)
  • DTXSID90232116 Edit this at Wikidata
SMILES
  • COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC
Properties
Chemical formula
C14H13NO4
Molar mass 259.261 g·mol−1
Melting point 177 °C (351 °F; 450 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Skimmianine is a furoquinoline alkaloid found in Skimmia japonica, a flowering plant in family Rutaceae that is native to Japan and China. It is also a strong acetylcholinesterase (AChE) inhibitor.[2]

  1. ^ "Chemistry Dashboard". comptox.epa.gov. Retrieved 2019-06-10.
  2. ^ Yang, Zhong-duo; Zhang, Dong-bo; Ren, Jin; Yang, Ming-jun (2012). "Skimmianine, a furoquinoline alkaloid from Zanthoxylum nitidum as a potential acetylcholinesterase inhibitor". Medicinal Chemistry Research. 21 (6): 722–725. doi:10.1007/s00044-011-9581-9. S2CID 14113860.

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