Secofentanyl is an opioid derivative which is an analogue of fentanyl where the piperidine ring has been cleaved to form an open-chain structure. It is around 40× less potent than fentanyl itself but still 5–6× the potency of morphine in animal tests.[1][2]
^Ivanović MD, Mićović I, Vučković S, Prostran M, Todorović Z, Ivanović E, Kiricojević V, Đorđević JB, Došen-Mićović L (2004). "The synthesis and pharmacological evaluation of (+/-)-2, 3-seco-fentanyl analogues". Journal of the Serbian Chemical Society. 69 (11): 955–68. doi:10.2298/JSC0411955I.
^Lipiński PF, Kosson P, Matalińska J, Roszkowski P, Czarnocki Z, Jarończyk M, Misicka A, Dobrowolski JC, Sadlej J (February 2019). "Fentanyl Family at the Mu-Opioid Receptor: Uniform Assessment of Binding and Computational Analysis". Molecules (Basel, Switzerland). 24 (4): 740. doi:10.3390/molecules24040740. PMC 6412969. PMID 30791394.
Secofentanyl is an opioid derivative which is an analogue of fentanyl where the piperidine ring has been cleaved to form an open-chain structure. It is...
Acetylfentanyl Benzylfentanyl Butyrylfentanyl Fentanyl azepane Isofentanyl Secofentanyl OPPPP Cooper D, Jacob M, Allen A (April 1986). "Identification of fentanyl...
much weaker, only around the same potency as morphine. Fentanyl azepane Secofentanyl Phenaridine List of fentanyl analogues Riley TN, Bagley JR (October 1979)...
α-Methylacetylfentanyl 4-Methylphenethylacetylfentanyl Homofentanyl Secofentanyl List of fentanyl analogues Drug Enforcement Administration, Department...
is controlled in most countries in the same fashion as is morphine. Secofentanyl Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes...