Sauvagine is a neuropeptide from the corticotropin-releasing factor (CRF) family of peptides and is orthologous to the mammalian hormone, urocortin 1, and the teleost fish hormone, urotensin 1.[1] It is 40 amino acids in length,[2] and has the sequence XGPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2, with a pyrrolidone carboxylic acid modification at the N-terminal and amidation of the C-terminal isoleucine residue. It was originally isolated from the skin of the frog Phyllomedusa sauvagii. Given its relation to other CRF-related peptides, it exerts similar physiological effects as corticotropin-releasing hormone.[3][4]
Sauvagine belongs to the corticotropin-releasing factor (CRF) family that also includes CRF, urocortin l/urotensin l, urocortin II and urocortin III.[5][1]
^ abLovejoy DA, de Lannoy L (December 2013). "Evolution and phylogeny of the corticotropin-releasing factor (CRF) family of peptides: expansion and specialization in the vertebrates". Journal of Chemical Neuroanatomy. 54: 50–6. doi:10.1016/j.jchemneu.2013.09.006. PMID 24076419. S2CID 24576375.
^Montecucchi PC, Henschen A (August 1981). "Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of Phyllomedusa sauvagei". International Journal of Peptide and Protein Research. 18 (2): 113–20. doi:10.1111/j.1399-3011.1981.tb02047.x. PMID 7309372.
^Falaschi P, D'Urso R, Negri L, Rocco A, Montecucchi PC, Henschen A, Melchiorri P, Erspamer V (August 1982). "Potent in vivo and in vitro prolactin inhibiting activity of sauvagine, a frog skin peptide". Endocrinology. 111 (2): 693–5. doi:10.1210/endo-111-2-693. PMID 7094889.
^Brown MR, Fisher LA, Spiess J, Rivier J, Rivier C, Vale W (July 1982). "Comparison of the biologic actions of corticotropin-releasing factor and sauvagine". Regulatory Peptides. 4 (2): 107–14. doi:10.1016/0167-0115(82)90101-X. PMID 6289384. S2CID 22063430.
^Fekete EM, Zorrilla EP (April 2007). "Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs". Frontiers in Neuroendocrinology. 28 (1): 1–27. doi:10.1016/j.yfrne.2006.09.002. PMC 2730896. PMID 17083971.
Sauvagine is a neuropeptide from the corticotropin-releasing factor (CRF) family of peptides and is orthologous to the mammalian hormone, urocortin 1...
corticotropin-releasing factor (CRF) family of proteins which includes CRF, urotensin I, sauvagine, urocortin II and urocortin III. Urocortin is involved in the mammalian...
Haxall's Moses Mare by Haxall's Moses 7 Salvator France Ch.c. 1872 Dollar x Sauvagine by Ion 7 Viani Italy B.c. 1967 Acropolis x Violante Vanni by Yorick 7...
anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene...
kind of a "holy relic". Précieuse, sword of Baligant, Emir of Babylon. Sauvagine, second of the two magical swords of Ogier the Dane. Colada, the other...
Cambridge University Press. pp. 642–653. Blondel, J. (1963). Situation de la sauvagine dans le Maghreb. In : Proceedings of the first European meeting on waterfowl...
Agnelles (2002) Drôle de tribu (2003) Seuls sont les indomptés (2005) La Sauvagine (2007) "Claude Courchay". Babelio (in French). "Monsieur Jean-Claude COURCHAY"...
"Christophe" "La Complainte du Folkloriste" "Le Rap à Ti-Pétang" "Reel de la Sauvagine" "Dans nos Vieilles Maisons" Musical direction: Jean Fréchette Engineered...
Sorel, Bécancour, Lévis Parc du Canal de Beauharnois, La Riveraine, La Sauvagine, Circuit des Traditions 4 Mauricie, Centre-du-Québec, Montérégie, Estrie...
corticotropin-releasing hormone family. This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally...
that in humans is encoded by the UCN2 gene. This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally...
anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene...
Global Information