Salsoline information

Salsoline
	; (±)-Salsoline
Names
	IUPAC name 6-Hydroxy-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
Identifiers
CAS Number	(±): 76419-97-1; (R)-(+): 101467-40-7; (S)-(–): 89-31-6 ;
3D model (JSmol)	(±): Interactive image; (S)-(–): Interactive image;
PubChem CID	(±): 46695; (R)-(+): 40010; (S)-(–): 442356;
UNII	(R)-(+): 9Q83ETU10C; (S)-(–): T246JT0V8K ;
	InChI (S)-(–): InChI=1S/C11H15NO2/c1-7-9-6-11(14-2)10(13)5-8(9)3-4-12-7/h5-7,12-13H,3-4H2,1-2H3;
	SMILES (±): CC1C2=CC(=C(C=C2CCN1)O)OC; (S)-(–): C[C@H]1NCCC2=CC(O)=C(C=C12)OC;
Properties
Chemical formula	C11H15NO2
Molar mass	193.246 g·mol−1
Appearance	White or almost white crystalline powder
Density	1.106 g/cm3
Melting point	217-219 °C
Solubility	Soluble in chloroform; slightly soluble in water, benzene
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	May cause allergic reaction. Avoid contact with eyes May cause eye irritation; May cause allergic reaction. May cause skin irritation; May be harmful if swallowed; May cause irritation of respiratory tract;
Flash point	157.4 °C (315.3 °F; 430.5 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Salsoline is a tetrahydroisoquinoline alkaloid found in some plants of the genus Salsola. Salsoline is the monomethylated metabolite of salsolinol which has been thought to contribute to Parkinson's disease.^{[medical citation needed]} Also, this has been tied to the neuropathology of chronic alcoholism.^[1]

^ Borg, S.; Kvande, H.; Magnuson, E.; Sjöqvist, B. (October 1980). "Salsolinol and Salsoline in Cerebrospinal Lumbar Fluid of Alcoholic Patients". Acta Psychiatrica Scandinavica. 62: 171–177. doi:10.1111/j.1600-0447.1980.tb08064.x. PMID 6935920. S2CID 33979452.

[borg-1] Borg, S.; Kvande, H.; Magnuson, E.; Sjöqvist, B. (October 1980). "Salsolinol and Salsoline in Cerebrospinal Lumbar Fluid of Alcoholic Patients". Acta Psychiatrica Scandinavica. 62: 171–177. doi:10.1111/j.1600-0447.1980.tb08064.x. PMID 6935920. S2CID 33979452.

Salsoline information

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Salsoline

Alkaloid

Tetrahydroisoquinoline

Bobbitt reaction

Salsola melitensis

Names
(±)-Salsoline
IUPAC name 6-Hydroxy-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
Identifiers
CAS Number	(±): 76419-97-1 (R)-(+): 101467-40-7 (S)-(–): 89-31-6^Y
3D model (JSmol)	(±): Interactive image (S)-(–): Interactive image
PubChem CID	(±): 46695 (R)-(+): 40010 (S)-(–): 442356
UNII	(R)-(+): 9Q83ETU10C (S)-(–): T246JT0V8K^Y
InChI (S)-(–): InChI=1S/C11H15NO2/c1-7-9-6-11(14-2)10(13)5-8(9)3-4-12-7/h5-7,12-13H,3-4H2,1-2H3
SMILES (±): CC1C2=CC(=C(C=C2CCN1)O)OC (S)-(–): C[C@H]1NCCC2=CC(O)=C(C=C12)OC
Properties
Chemical formula	C₁₁H₁₅NO₂
Molar mass	193.246 g·mol⁻¹
Appearance	White or almost white crystalline powder
Density	1.106 g/cm³
Melting point	217-219 °C
Solubility	Soluble in chloroform; slightly soluble in water, benzene
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	May cause allergic reaction. Avoid contact with eyes May cause eye irritation May cause allergic reaction. May cause skin irritation May be harmful if swallowed May cause irritation of respiratory tract
Flash point	157.4 °C (315.3 °F; 430.5 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references