Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen fruit peel in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic, metabolic, and genetic properties,[1]S. boulardii is genetically a grouping of S. cerevisiae strains, sharing >99% genomic relatedness, giving the synonym S. cerevisiae var. boulardii.[2][3][4]
S. boulardii is sometimes used as a probiotic with the purpose of introducing beneficial microbes into the large and small intestines and conferring protection against pathogens.[5][6][7] It grows at 37 °C (98.6 °F).[8] In addition, the popular genome-editing tool CRISPR-Cas9 was proven to be effective in S. boulardii.[9] Boulard first isolated this yeast after he observed natives of Southeast Asia chewing on the skin of lychee and mangosteen in an attempt to control the symptoms of cholera. In healthy patients, S. boulardii has been shown to be nonpathogenic and nonsystemic (it remains in the gastrointestinal tract rather than spreading elsewhere in the body).
^Malgoire JY, Bertout S, Renaud F, Bastide JM, Mallié M (March 2005). "Typing of Saccharomyces cerevisiae clinical strains by using microsatellite sequence polymorphism". Journal of Clinical Microbiology. 43 (3): 1133–1137. doi:10.1128/JCM.43.3.1133-1137.2005. PMC 1081240. PMID 15750073.
^Khatri I, Tomar R, Ganesan K, Prasad GS, Subramanian S (March 2017). "Complete genome sequence and comparative genomics of the probiotic yeast Saccharomyces boulardii". Scientific Reports. 7 (1): 371. Bibcode:2017NatSR...7..371K. doi:10.1038/s41598-017-00414-2. PMC 5428479. PMID 28336969. [Note on source: The authors assign strain names based on the supplier of the probiotic. Of these suppliers, Biocodex and EDRL both claim to use the CNCM I-745 strain on their website.]
^Rajkowska K, Kunicka-Styczyńska A (January 2009). "Phenotypic and genotypic characterization of probiotic yeasts". Biotechnology & Biotechnological Equipment. 23 (supplement 1): 662–5. doi:10.1080/13102818.2009.10818511. S2CID 84649167.
^Łukaszewicz M (2012). "Chapter 16: Saccharomyces cerevisiae var. boulardii – Probiotic Yeast". In Rigobelo EC (ed.). Probiotics. pp. 385–98. ISBN 978-953-51-0776-7.
^Rajkowska K, Kunicka-Styczyńska A (April 2012). "Probiotic Activity of Saccharomyces cerevisiae var. boulardii Against Human Pathogens" (PDF). Food Technology and Biotechnology. 50: 230–36. Retrieved 18 January 2014.
^Toma MM, Raipulis J, Kalnina I, Rutkis R (June 2005). "Effect of Probiotic Yeast on Genotoxicity" (PDF). Food Technology and Biotechnology. 43: 301–05. Retrieved 18 January 2014.
^Soccol CR, Vandenberghe LP, Spier MR, Medeiros AB, Yamaguishi CT, Lindner JD, Pandey A, Thomaz-Soccol V (June 2010). "The Potential of Probiotics: A Review" (PDF). Food Technology and Biotechnology. 48: 413–34. Retrieved 18 January 2014.
^McFarland LV, Bernasconi P (1993). "Saccharomyces boulardii: a review of an innovative biotherapeutic agent". Microb Ecol Health Dis. 6 (4): 157–71. doi:10.3109/08910609309141323.
^Liu JJ, Kong II, Zhang GC, Jayakody LN, Kim H, Xia PF, et al. (April 2016). "Metabolic Engineering of Probiotic Saccharomyces boulardii". Applied and Environmental Microbiology. 82 (8): 2280–2287. Bibcode:2016ApEnM..82.2280L. doi:10.1128/AEM.00057-16. PMC 4959471. PMID 26850302.
and 28 Related for: Saccharomyces boulardii information
Saccharomycesboulardii is a tropical yeast first isolated from lychee and mangosteen fruit peel in 1923 by French scientist Henri Boulard. Although early...
into the water. Saccharomyces cerevisiae is used as a probiotic in humans and animals. The strain Saccharomyces cerevisiae var. boulardii is industrially...
Saccharomyces is a genus of fungi that includes many species of yeasts. Saccharomyces is from Greek σάκχαρον (sugar) and μύκης (fungus) and means sugar...
1% and Saccharomyces as the fourth most common.[citation needed] However, the frequency of infection by C. glabrata, Saccharomycesboulardii, Candida...
Yargic ZA, Vandenplas Y (2012). "Effectiveness and safety of Saccharomycesboulardii for acute infectious diarrhea". Expert Opinion on Biological Therapy...
Henri Boulard was a French microbiologist who discovered the yeast Saccharomycesboulardii in 1923. He noticed people chewing on the skins of lychees and...
probiotics that may help ease symptoms of IBS. A probiotic yeast called Saccharomycesboulardii has some evidence of effectiveness in the treatment of irritable...
with a vancomycin taper supplemented with probiotics, especially Saccharomycesboulardii, is associated with a higher rate of success. After three relapses...
antinutrient phytic acid. Aspergillus oryzae Medicinal molds SaccharomycesboulardiiSaccharomyces cerevisiae Shurtleff, W. & Aoyagi, A. 2001. The book of...
and dosage. One review recommended for children L. rhamnosus or Saccharomycesboulardii at 5 to 40 billion colony-forming units/day, given the modest number...
antibiotic-associated diarrhea and that taking probiotics with Saccharomyces (e.g., Saccharomycesboulardii ) may help to prevent Clostridium difficile infection...
administration of specific probiotics such as Lactobacillus rhamnosus or Saccharomycesboulardii, diosmectite or racecadotril." Rotaviruses are highly contagious...
and management of SIBO. Conversely, Lactobacillus fermentum and Saccharomycesboulardii have been found to be ineffective.[failed verification] A combination...
out. Some studies have recently evaluated the role of the yeast Saccharomycesboulardii as a coadjutant in the eradication of H. pylori and in the prevention...
treatment with orally administered mixtures of P. acidilactici and Saccharomycesboulardii, the dogs diagnosed with parvovirus infection were shown to exhibit...
of recurrent Clostridium difficile colitis with vancomycin and Saccharomycesboulardii". The American Journal of Gastroenterology. 84 (10): 1285–7. PMID 2679049...
be useful to prevent infection and recurrence. Treatment with Saccharomycesboulardii in those who are not immunocompromised with C. difficile also may...
significant difference in the protective effect of strains, namely Saccharomycesboulardii, Lactobacillus rhamnosus GG, Lactobacillus acidophilus, and Lactobacillus...
preparations such as Lactobacillus rhamnosus (a bacterium) and Saccharomycesboulardii (a yeast) may be effective at reducing the duration and severity...
in vitro study. There is also evidence that the probiotic yeast Saccharomycesboulardii, and the plant mallotus oppositifolius may be effective against...
good results on abdominal symptoms. It is advised to administer Saccharomycesboulardii once a day during this course of antibiotherapy. Doxycycline resistance...
inflammation in mouse models of inflammatory bowel disease. A live S. boulardii yeast delivering a tetra-specific anti-toxin that potently neutralizes...
Global Information