STK24 information

STK24
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3A7F, 3A7G, 3A7H, 3A7I, 3A7J, 3CKW, 3CKX, 3ZHP, 4O27, 4QML, 4QMM, 4QMN, 4QMO, 4QMP, 4QMQ, 4QMS, 4QMT, 4QMU, 4QMV, 4QMW, 4QMX, 4QMY, 4QMZ, 4QO9, 4U8Z, 4W8D, 4W8E, 4QNA
Identifiers
Aliases	STK24, HEL-S-95, MST3, MST3B, STE20, STK3, serine/threonine kinase 24
External IDs	OMIM: 604984; MGI: 2385007; HomoloGene: 20793; GeneCards: STK24; OMA:STK24 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	98,577,940 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	121,617,423 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; amniotic fluid; ; pancreatic ductal cell; ; retinal pigment epithelium; ; gingival epithelium; ; endothelial cell; ; hair follicle; ; palpebral conjunctiva; ; germinal epithelium; ; skin of thigh;
	Top expressed in
	blood; ; ascending aorta; ; granulocyte; ; tail of embryo; ; aortic valve; ; transitional epithelium of urinary bladder; ; mesenteric lymph nodes; ; cumulus cell; ; genital tubercle; ; skin of external ear;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; metal ion binding; kinase activity; protein binding; ATP binding; protein kinase activity; protein serine/threonine kinase activity; cadherin binding; MAP kinase kinase kinase kinase activity;
Cellular component	membrane; nucleoplasm; nucleolus; extracellular exosome; nucleus; cytosol; cytoplasm; Golgi apparatus;
Biological process	intrinsic apoptotic signaling pathway in response to oxidative stress; regulation of axon regeneration; phosphorylation; negative regulation of cell migration; response to hydrogen peroxide; signal transduction; apoptotic process; protein phosphorylation; execution phase of apoptosis; cellular response to starvation; protein autophosphorylation; MAPK cascade; regulation of mitotic cell cycle; stress-activated protein kinase signaling cascade; regulation of apoptotic process; neuron projection morphogenesis; activation of protein kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	8428
	223255
	ENSG00000102572
	ENSMUSG00000063410
	Q9Y6E0; Q5JV99
	Q99KH8
	NM_001032296; NM_001286649; NM_003576
	NM_145465
	NP_001027467; NP_001273578; NP_003567
	NP_663440
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase 24 is an enzyme that in humans is encoded by the STK24 gene^[5]^[6]^[7] located in the chromosome 13, band q32.2. It is also known as Mammalian STE20-like protein kinase 3 (MST-3).^[8] The protein is 443 amino acids long and its mass is 49 kDa.^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102572 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000063410 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schinkmann K, Blenis J (November 1997). "Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements". The Journal of Biological Chemistry. 272 (45): 28695–703. doi:10.1074/jbc.272.45.28695. PMID 9353338.
^ Zhou TH, Ling K, Guo J, Zhou H, Wu YL, Jing Q, Ma L, Pei G (January 2000). "Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase". The Journal of Biological Chemistry. 275 (4): 2513–9. doi:10.1074/jbc.275.4.2513. PMID 10644707.
^ "Entrez Gene: STK24 serine/threonine kinase 24 (STE20 homolog, yeast)".
^ ^a ^b "STK24 - Serine/threonine-protein kinase 24 - Homo sapiens (Human) - STK24 gene & protein". www.uniprot.org. Retrieved 2018-11-10.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000102572 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000063410 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9353338-5] Schinkmann K, Blenis J (November 1997). "Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements". The Journal of Biological Chemistry. 272 (45): 28695–703. doi:10.1074/jbc.272.45.28695. PMID 9353338.

[Zhou_2000-6] Zhou TH, Ling K, Guo J, Zhou H, Wu YL, Jing Q, Ma L, Pei G (January 2000). "Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase". The Journal of Biological Chemistry. 275 (4): 2513–9. doi:10.1074/jbc.275.4.2513. PMID 10644707.

[entrez-7] "Entrez Gene: STK24 serine/threonine kinase 24 (STE20 homolog, yeast)".

[UniProt_Q9Y6E0-8] "STK24 - Serine/threonine-protein kinase 24 - Homo sapiens (Human) - STK24 gene & protein". www.uniprot.org. Retrieved 2018-11-10.

STK24 information

and 15 Related for: STK24 information

STK24

Housekeeping gene

Proser2

Protein kinase domain

PPP2R1A

FGFR1OP2

STRN4

STRN

PDCD10

TRAF3IP3

CTTNBP2NL

SLMAP

STRN3

FAM40A

MOBKL3