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Rosiridin information


Rosiridin
Names
IUPAC name
(2R,3R,4S,5S,6R)-2-{[(2E,4S)-4-Hydroxy-3,7-dimethylocta-2,6-dien-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
Identifiers
CAS Number
  • 100462-37-1
3D model (JSmol)
  • Interactive image
PubChem CID
  • 25068281
UNII
  • 71AL4K0H19 checkY
CompTox Dashboard (EPA)
  • DTXSID80438024 Edit this at Wikidata
SMILES
  • CC(=CC[C@@H](/C(=C/CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)/C)O)C
Properties
Chemical formula
C16H28O7
Molar mass 332.393 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Rosiridin is a chemical compound that has been isolated from Rhodiola sachalinensis.[1] Rosiridin can inhibit monoamine oxidases A and B, possibly meaning that the compound could help in the treatment of depression and senile dementia.[2][3]

  1. ^ Yoshikawa, Masayuki; Nakamura, Seikou; Li, Xuezheng; Matsuda, Hisashi (2008). "Reinvestigation of absolute stereostructure of (−)-rosiridol: Structures of monoterpene glycosides, rosiridin, rosiridosides A, B, and C, from Rhodiola sachalinesnsis". Chemical and Pharmaceutical Bulletin. 56 (5): 695–700. doi:10.1248/cpb.56.695. PMID 18451561.
  2. ^ Panossian, Alexander; Wikman, Georg (2010). "Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress-protective activity". Pharmaceuticals. 3 (1): 188–224. doi:10.3390/ph3010188. PMC 3991026. PMID 27713248.
  3. ^ van Diermen, Daphne; Marston, Andrew; Bravo, Juan; Reist, Marianne; Carrupt, Pierre-Alain; Hostettmann, Kurt (2009-03-18). "Monoamine oxidase inhibition by Rhodiola rosea L. roots". Journal of Ethnopharmacology. 122 (2): 397–401. doi:10.1016/j.jep.2009.01.007. ISSN 0378-8741.

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Rosiridin

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Rosiridin is a chemical compound that has been isolated from Rhodiola sachalinensis. Rosiridin can inhibit monoamine oxidases A and B, possibly meaning...

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Rhodiola rosea

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and salidroside (and sometimes p-tyrosol, rhodioniside, rhodiolin, and rosiridin) are among suspected active ingredients of R. rosea, these compounds are...

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Monoamine oxidase inhibitor

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Pirlindole (Pirazidol) Naturally occurring RIMAs in plants Harmaline Harmine Rosiridin (in vitro) Research compounds Amiflamine (FLA-336) Befloxatone (MD-370...

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Monoamine oxidase A

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Ayahuasca) Harmine Harmaline Isoquinoline alkaloids Piperine (Black pepper) Rosiridin (in vitro) Monoamine oxidase B Monoamine oxidase inhibitor - a class of...

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Monoamine oxidase B

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extract; modest affinity Catechin and epicatechin[citation needed]. Garlic Rosiridin (in vitro) Safinamide and analogs 5H-Indeno[1,2-c]pyridazin-5-ones (see...

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