Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Rhodanine is a 5-membered heterocyclic organic compound possessing a thiazolidine core. It was discovered in 1877 by Marceli Nencki who named it "Rhodaninsaure" in reference to its synthesis from ammonium rhodanide (known as ammonium thiocyanate to modern chemists) and chloroacetic acid in water.[3]
Rhodanines can also be prepared by the reaction of carbon disulfide, ammonia, and chloroacetic acid, which proceeds via an intermediate dithiocarbamate.[4]
^Rhodanine at Sigma-Aldrich
^ abcdHaynes, William M., ed. (2011). CRC Handbook of Chemistry and Physics (92nd ed.). CRC Press. p. 3.512. ISBN 978-1439855119.
^Nencki, M. (10 July 1877). "Ueber die Einwirkung der Monochloressigsäure auf Sulfocyansäure und ihre Salze". Journal für Praktische Chemie. 16 (1): 1–17. doi:10.1002/prac.18770160101.
^Redemann, C. Ernst; Icke, Roland N.; Alles, Gordon A. (1955). "Rhodanine". Organic Syntheses; Collected Volumes, vol. 3, p. 763.
Rhodanine is a 5-membered heterocyclic organic compound possessing a thiazolidine core. It was discovered in 1877 by Marceli Nencki who named it "Rhodaninsaure"...
one oxygen atom in a thiazolidinedione with an atom of sulfur gives a rhodanine. The only approved use of the thiazolidinediones is in diabetes mellitus...
thiazolidinediones, are drugs used in the treatment of diabetes mellitus type 2. Rhodanine is a related bioactive species, featuring one carbonyl and one thiocarbonyl...
Chemically, epalrestat is unusual in that it is a drug that contains a rhodanine group. Aldose reductase is the key enzyme in the polyol pathway whose...
008.0074. C. Ernst Redemann, Roland N. Icke, Gordon A. Alles (1947). "Rhodanine". Organic Syntheses. 27: 73. doi:10.15227/orgsyn.027.0073.{{cite journal}}:...
made up to 50 ml with water. Then 1.5 ml of freshly prepared 0.667% w/v rhodanine in methanol and 1 ml of sample are mixed. After exactly 5 min 1 ml of...
PYP to specifically and reversibly bind a series of hydroxybenzylidene rhodanine (HBR) derivatives for their fluorogenic properties. Upon interaction with...
units. In 1877 while working at the University of Berne he discovered rhodanine via a reaction between ammonium rhodanide (in modern chemistry ammonium...
that it is accompanied by binding of carbon dioxide. He also discovered rhodanine in 1877. Bohdan Szyszkowski, Polish chemist and member of Polish Academy...
catechins as anti-cancer and antimalarial agents. He has developed a rhodanine, BCFMT, as a potential therapeutic for cancer. Surolia co-discovered the...
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