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Remethylation information


Remethylation involves methylation that occurs in some biochemical cycles. Often methyl groups are not mobile when attached to nitrogen and sulfur, but the removal and reinstallation of methyl groups does occur with the assistance of certain enzymes.

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Remethylation

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Remethylation involves methylation that occurs in some biochemical cycles. Often methyl groups are not mobile when attached to nitrogen and sulfur, but...

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Trimethylglycine

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DNA for epigenetics. The major step in the methylation cycle is the remethylation of homocysteine, a compound which is naturally generated during demethylation...

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Methylenetetrahydrofolate reductase

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to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Natural variation in this gene is common in otherwise...

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Methylation

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– a biophysical method to determine the methylisation state of DNA Remethylation, the reversible removal of methyl group in methionine and 5-methylcytosine...

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Hyperhomocysteinemia

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of homocysteine [citation needed] is converted back to methionine by remethylation via the methionine synthase major pathway. This requires active folate...

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Reprogramming

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early embryogenesis, and again in gametogenesis, with demethylation and remethylation occurring each time. Demethylation during early embryogenesis occurs...

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Folate

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Baumgartner MR (July 2019). "Vitamin B12, folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation". Journal of Inherited...

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Vitamin B12

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Baumgartner MR (July 2019). "Vitamin B12, folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation" (PDF). Journal of Inherited...

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Vitamin B12 deficiency

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lower cardiovascular disease. Deficiency of vitamin B12 can impair the remethylation of homocysteine in the methionine cycle, and result in raised homocysteine...

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DNA methylation

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gametogenesis, and again in early embryogenesis, with demethylation and remethylation occurring each time. Demethylation in early embryogenesis occurs in...

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Methionine synthase

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"Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida". American Journal of Human Genetics...

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MTHFD2L

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pathway can contribute to purine and thymidine synthesis and homocysteine remethylation into methionine, as well as be converted into 1-carbon units to fuel...

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Neuroepigenetics

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certain recurring stimuli leads to demethylation of particular loci and remethylation in a pattern that leads to a response to that particular stimulus. Like...

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Gaseous signaling molecules

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Christensen B, Refsum H, Garras A, Ueland PM (Jun 1992). "Homocysteine remethylation during nitrous oxide exposure of cells cultured in media containing...

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GNMT

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contents and folate-dependent methionine synthase-mediated homocysteine remethylation". Molecular Medicine. 17 (5–6): 486–94. doi:10.2119/molmed.2010.00243...

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