Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene.[5][6]
The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000143248 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000026678 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Seki N, Sugano S, Suzuki Y, Nakagawara A, Ohira M, Muramatsu M, Saito T, Hori T (October 1998). "Isolation, tissue expression, and chromosomal assignment of human RGS5, a novel G-protein signaling regulator gene". J Hum Genet. 43 (3): 202–5. doi:10.1007/s100380050071. PMID 9747037.
^ ab"Entrez Gene: RGS5 regulator of G-protein signalling 5".
Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene. The regulator of G protein signaling (RGS) proteins are signal transduction...
Epididymal basal cell Endothelial cells circulatory system ABCC9, KCNJ8, RGS5 Planum semilunar epithelial cell of vestibular system of ear (proteoglycan...
has been shown to interact with: RGS10 RGS12, RGS14, RGS16, RGS18, RGS19, RGS5, RIC8A, and S1PR1. Gi alpha subunit GRCh38: Ensembl release 89: ENSG00000065135...
to cause epileptic encephalopathy. GNAO1 has been shown to interact with: RGS5, RGS19, RGS20, and RIC8A GRCh38: Ensembl release 89: ENSG00000087258 – Ensembl...