positive regulation of insulin secretion involved in cellular response to glucose stimulus
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
5879
19353
Ensembl
ENSG00000136238
ENSMUSG00000001847
UniProt
P63000
P63001
RefSeq (mRNA)
NM_198829 NM_006908 NM_018890
NM_009007 NM_001347530
RefSeq (protein)
NP_008839 NP_061485
NP_001334459 NP_033033
Location (UCSC)
Chr 7: 6.37 – 6.4 Mb
Chr 5: 143.49 – 143.51 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells. It is encoded by the RAC1 gene.[5][6] This gene can produce a variety of alternatively spliced versions of the Rac1 protein, which appear to carry out different functions.[7]
^ abcGRCh38: Ensembl release 89: ENSG00000136238 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000001847 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Didsbury J, Weber RF, Bokoch GM, Evans T, Snyderman R (Oct 1989). "rac, a novel ras-related family of proteins that are botulinum toxin substrates". The Journal of Biological Chemistry. 264 (28): 16378–82. doi:10.1016/S0021-9258(19)84716-6. PMID 2674130.
^Jordan P, Brazåo R, Boavida MG, Gespach C, Chastre E (Nov 1999). "Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors". Oncogene. 18 (48): 6835–9. doi:10.1038/sj.onc.1203233. PMID 10597294.
^Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Showe LC, Liu Q, Vachani A, Albelda SM, Kissil JL (Feb 2013). "The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis". Oncogene. 32 (7): 903–9. doi:10.1038/onc.2012.99. PMC 3384754. PMID 22430205.
Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells. It is encoded by the RAC1 gene. This gene can produce...
plants. Three members of the family have been studied in detail: Cdc42, Rac1, and RhoA. All G proteins are "molecular switches", and Rho proteins play...
The human PAK1 was identified as a GTP-dependent interacting partner of Rac1 or Cdc42 in the cytosolic fraction from neutrophils, and its complementary...
stimulates GLUT4 to be expressed on the plasma membrane. RAC1 is a GTPase also activated by insulin. Rac1 stimulates reorganization of the cortical Actin cytoskeleton...
is the most listened-to radio program in Catalonia. El món a RAC1 Minoria Absoluta Versió Rac1 Primer Toc Tu diràs List of radio stations in Catalan...
2023. "Andrea Pirlo, nou fitxatge de Gerard Romero per a la Kings League". RAC1 (in Catalan). 30 May 2023. Pérez, Juan (12 June 2023). "Shevchenko ficha...
12, 2018. ""Em sento català, fins i tot he cantat Havaneres a Calella!"". rac1.org. Retrieved September 6, 2015. "The Ghostman and Demon Hunter Show "The...
Benidorm Fest: "El nostre nom és una picada d'ullet al català"" (in Catalan). RAC1. Retrieved 4 February 2024. Díaz, Domingo (11 February 2024). "La vida antes...
after 14.Bxb4 Qxb4 15.a3 Qe7 16.Rac1 0-0 17.Qc7! with an unpleasant grip.) 14. Be3! (Threatening to win outright with 15.Rac1. Black must do something about...
tumour suppressor genes. Another possible mechanism of carcinogenesis is RAC1 activation by a small GTPase-like protein fragment of Mycoplasma. A major...
GTPase-activating protein for members of the Rho family of GTPases such as RAC1. YopT is a cysteine protease that inhibits RhoA by removing the isoprenyl...
(PI3Ks). In neutrophils, lipid products of PI3Ks regulate activation of Rac1, hematopoietic Rac2, and RhoG GTPases of the Rho family and are required...
adaptive immune responses of the host. YopE targets the small GTPases: RhoA, Rac1, and Rac2. YopE GAP activity inhibits two common methods of host immunity...
heterodimer and a WAVE1-Abi2-HSPC300 heterotrimer, and following interaction with Rac1, the holocomplex has been observed in a CYFIP1-Nap1-Abi2 heterotrimer subcomplex...
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an...
phosphoinositol-3-phosphate or neutral membranes. Members of the Rho GTPase family (e.g., Rac1, Rac2, Rac3, and cdc42) have been implicated in their activation by binding...
d'Alèxia Putellas destrona la de Messi: aquestes són les més demanades". RAC1 (in Catalan). 6 April 2022. Retrieved 4 December 2022. "Alexia Putellas estrena...
"Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth". The Journal...
"Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA". J. Biol. Chem. 266 (15): 9786–94. doi:10.1016/S0021-9258(18)92889-9...
CA (August 2013). "Study of vaccinia and cowpox viruses' replication in Rac1-N17 dominant-negative cells". Memórias do Instituto Oswaldo Cruz. 108 (5):...