Global InformationPyranose oxidase information
| pyranose oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Pyranose oxidase tetramer, Trametes ochracea | |||||||||
| Identifiers | |||||||||
| EC no. | 1.1.3.10 | ||||||||
| CAS no. | 37250-80-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a pyranose oxidase (EC 1.1.3.10) is an enzyme that catalyzes the chemical reaction
- D-glucose + O2 2-dehydro-D-glucose + H2O2
Thus, the two substrates of this enzyme are D-glucose and O2, whereas its two products are 2-dehydro-D-glucose and H2O2.
Pyranose oxidase is able to oxidize D-xylose, L-sorbose, D-galactose,[1] and D-glucono-1,5-lactone, which have the same ring conformation and configuration at C-2, C-3 and C-4.[2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyranose:oxygen 2-oxidoreductase. Other names in common use include glucose 2-oxidase, and pyranose-2-oxidase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, FAD.
- ^ Abrera AT, Sützl L, Haltrich D (April 2020). "Pyranose oxidase: A versatile sugar oxidoreductase for bioelectrochemical applications". Bioelectrochemistry. 132: 107409. doi:10.1016/j.bioelechem.2019.107409. PMID 31821902.
- ^ Janssen FW, Ruelius HW (November 1968). "Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. II. Specificity and characterization of reaction products". Biochimica et Biophysica Acta (BBA) - Enzymology. 167 (3): 501–10. doi:10.1016/0005-2744(68)90040-5. PMID 5722278.