Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
PyBOP (benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent used in solid phase peptide synthesis. It is used as a substitute for the BOP reagent - avoiding the formation of the carcinogenic waste product HMPA.[3]
^Sigma-Aldrich Co., product no. {{{id}}}.
^GHS: Sigma-Aldrich377848
^Coste, J.; Le-Nguyen, D.; Castro, B. (1990). "PyBOP®: A new peptide coupling reagent devoid of toxic by-product". Tetrahedron Letters. 31 (2): 205. doi:10.1016/S0040-4039(00)94371-5.
PyBOP (benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent used in solid phase peptide synthesis. It is used...
differ only in the choice of anion. Phosphonium reagents include PyBOP (HOBt) and PyAOP (HOAt).[citation needed] These reagents form the same active ester...
the reduction of carboxylic acids, using the BOP reagent with NaBH4 resulted in high percent yields. PyBOP, a related reagent "(Benzotriazol-1-yloxy)t...
HOBt derivates, PyAOP (and HOAt in general) are more reactive due to the additional nitrogen. HOAt reagent HOBt reagent BOP reagent PyBOP Albericio, F.;...
RC(O)NR'2 + RCO2H Peptide synthesis use coupling agents such as HATU, HOBt, or PyBOP. The hydrolysis of nitriles is conducted on an industrial scale to produce...
displaces the benzotriazole N-oxide to form the desired amide. EDC HATU BOP reagent PyBOPPyAOP reagent CID 2733084 from PubChem "2-(1h-Benzotriazole-1-yl)-1...
during SPPS, though the approach was regarded as 'costly and tedious'. BOPPyBOP Li, Haitao; Jiang, Xiaohui; Ye, Yun-hua; Fan, Chongxu; Romoff, Todd; Goodman...
tautomerizable heterocycle is activated with a phosphonium salt (PyBroP, PyBOP, BroP, or BOP), and subsequent functionalization with either a nucleophile...
amide Retosiban 8 by activating the acid with the peptide coupling reagent PyBOP (benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate) followed...
for Optimizing the Hyperparameters of Machine Learning Algorithms. Proc. SciPy 2013. Chris Thornton, Frank Hutter, Holger H. Hoos, Kevin Leyton-Brown: Auto-WEKA:...
(1977) Pistol Packin' Mama (1982) Pistol Packin' Mama/Spin of the Wheel (1998) Py Bäckman — P20Y10 (2010) Russ Ballard — At The Third Stroke (1978) Barefoot...
[ReOSe(2-pySe)3]; see Cargnelutti, Roberta; Lang, Ernesto S.; Piquini, Paulo; Abram, Ulrich (2014). "Synthesis and structure of [ReOSe(2-Se-py)3]: A rhenium(V)...
material released under their name is instrumental. The Meters (1969) Look-Ka PyPy (1969) Struttin' (1970) Cabbage Alley (1972) Rejuvenation (1974) Fire on...
2002 FAST FAST Alignment and Search Tool Cα Pair nil server J. Zhu 2004 C-BOP Coordinate-Based Organization of Proteins N/A Multi nil server E. Sandelin...