Protonitazepyne (N-pyrrolidino protonitazene) is a benzimidazole derivative with opioid effects, which has been sold as a designer drug over the internet, first being mentioned in mid 2022 and definitively identified in drug seizures in Canada in early 2023. It is an analogue of etonitazene where the ethoxy group has been extended to propoxy, and the N,N-diethyl substitution has been cyclised into a pyrrolidine ring. While formal studies into its pharmacology have yet to be carried out, it is believed to be slightly less potent than the ethoxy analogue etonitazepyne but still a potent opioid.[1][2]
^"Early signal alert: Emergence of online mentions of Protonitazepyne". National Drug Early Warning System. 29 July 2022.
^"Analyzed Drug Report" (PDF). Drug Analysis Service and Cannabis Laboratories. Health Canada. April–June 2023.
Protonitazepyne (N-pyrrolidino protonitazene) is a benzimidazole derivative with opioid effects, which has been sold as a designer drug over the internet...
a designer drug. Etazene Etonitazepyne Isotonitazene Metonitazene Protonitazepyne List of benzimidazole opioids Hunger A, Kebrle J, Rossi A, Hoffmann...
though it can be difficult to distinguish from the isomeric compound protonitazepyne. It is specifically listed as an illegal drug in the US state of Virginia...
refer to: Etonitazepipne (N-piperidino etonitazene) Isotonitazepyne Protonitazepyne This set index page lists chemical structure articles associated with...