Podophyllum resin, also known as podophyllum or podophyllin, is a resin made from the roots of the American mandrake.[1] It is used as a medication to treat genital warts and plantar warts, including in people with HIV/AIDS.[2][3] It is not recommended in HPV infections without external warts. Application by a healthcare provider to the skin is recommended.[2]
Common side effects include redness, itchiness, and pain at the site of use. Severe side effects may include vomiting, abdominal pain, confusion, bone marrow suppression, and diarrhea. It is not recommended for more than a small area at a time. Use during pregnancy is known to be dangerous to the baby.[2] It works mostly via podophyllotoxin which stops cell division.[1]
Podophyllin resin has been used to treat warts since at least 1820.[4] It is on the World Health Organization's List of Essential Medicines.[5][6] A formulation known as podophyllotoxin with less side effects is also available.[3]
^ abBriggs GG, Freeman RK, Yaffe SJ (2011). Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Lippincott Williams & Wilkins. p. 1190. ISBN 9781608317080. Archived from the original on 22 December 2016.
^ abc"Podophyllum Resin". The American Society of Health-System Pharmacists. Archived from the original on 22 December 2016. Retrieved 8 December 2016.
^ abWorld Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 307, 309. hdl:10665/44053. ISBN 9789241547659.
^Lata H, Chandra S (2010). "Biotechnological characterization of different populations of an endangered medicinal herb - Podophyllum hexandrum Royle". In Arora R (ed.). Medicinal plant biotechnology. CABI. p. 36. doi:10.1079/9781845936785.0036. ISBN 9781845936921.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
Podophyllumresin, also known as podophyllum or podophyllin, is a resin made from the roots of the American mandrake. It is used as a medication to treat...
extracted from the roots and rhizomes of Podophyllum species. A less refined form known as podophyllumresin is also available, but has greater side effects...
The rhizome of the plant also contains a resin, known generally and commercially as Indian PodophyllumResin, which can be processed to extract podophyllin...
stopped, or as the underlying immunocompromise worsens. Topical use of podophyllumresin or retinoids has also been reported to produce temporary remission...
dried roots and rhizomes or application of resin. Podophyllotoxin is a major active ingredient in Podophyllum pleianthum that is cytotoxic, arresting cellular...
quaternary ammonium anion exchange resin from the chloride form to the cyanate form with sodium cyanate and reacting the resin in the cyanate form with hydroxylamine...
Note on Resin-value of Podeophyllum emodi and the best season for collecting it by Puran Singh, Forest Bulletin (1912), No.9. 17. Podophyllum emodi by...
plantations. Paclitaxel is then captured directly from the suspension broth by a resin allowing concentration to highly enriched powder containing about 40% paclitaxel...
Contact with the milky latex may irritate eyes and skin.[citation needed] Podophyllum peltatum mayapple Berberidaceae Green portions of the plant, unripe fruit...
the resin of which was used by the Chippewa to treat infections and gangrene. Pluchea sericea, used as an antidiarrheal and eyewash. Podophyllum peltatum...
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