Global Information Lookup Global Information

Pittsburgh compound B information


Pittsburgh compound B
Names
Preferred IUPAC name
2-{4-[(11C)Methylamino]phenyl}-1,3-benzothiazol-6-ol
Other names
PiB
Identifiers
CAS Number
  • 566170-04-5 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 2104829 ☒N
PubChem CID
  • 2826731
UNII
  • 7P55415B0R checkY
CompTox Dashboard (EPA)
  • DTXSID00205194 Edit this at Wikidata
InChI
  • InChI=1S/C14H12N2OS/c1-15-10-4-2-9(3-5-10)14-16-12-7-6-11(17)8-13(12)18-14/h2-8,15,17H,1H3/i1-1 ☒N
    Key: ZQAQXZBSGZUUNL-BJUDXGSMSA-N ☒N
  • InChI=1/C14H12N2OS/c1-15-10-4-2-9(3-5-10)14-16-12-7-6-11(17)8-13(12)18-14/h2-8,15,17H,1H3/i1-1
    Key: ZQAQXZBSGZUUNL-BJUDXGSMEE
SMILES
  • [11CH3]NC1=CC=C(C=C1)C2=NC3=C(S2)C=C(C=C3)O
Properties
Chemical formula
C14H12N2OS
Molar mass 256.32 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Pittsburgh compound B (PiB) is a radioactive analog of thioflavin T, which can be used in positron emission tomography scans to image beta-amyloid plaques in neuronal tissue. Due to this property, Pittsburgh compound B may be used in investigational studies of Alzheimer's disease.

and 21 Related for: Pittsburgh compound B information

Request time (Page generated in 0.8377 seconds.)

Pittsburgh compound B

Last Update:

Pittsburgh compound B (PiB) is a radioactive analog of thioflavin T, which can be used in positron emission tomography scans to image beta-amyloid plaques...

Word Count : 1076

Positron emission tomography

Last Update:

University of California, Los Angeles and Pittsburgh compound B (PiB)developed at the University of Pittsburgh. These probes permit the visualization of...

Word Count : 8693

Henry Engler

Last Update:

healthy volunteers and Alzheimer's patients the substance PIB (Pittsburgh compound B) to detect amyloid plaques in the brain. The results were presented...

Word Count : 164

PIB

Last Update:

model quantum mechanical system Pebibyte (PiB), a unit of digital information storage Pittsburgh compound B (PiB), chemical used in studying Alzheimer's Disease...

Word Count : 162

Amyloid beta

Last Update:

crenezumab, gantenerumab, lecanemab, and solanezumab. Imaging compounds, notably Pittsburgh compound B, (6-OH-BTA-1, a thioflavin), can selectively bind to amyloid...

Word Count : 4769

Standardized uptake value

Last Update:

commonly abbreviated SUVR. An example is the ratio of regional Pittsburgh compound B PET signal intensity to the average signal of a much wider region...

Word Count : 1594

Dementia with Lewy bodies

Last Update:

are affected. Autopsy studies and amyloid imaging studies using Pittsburgh compound B (PiB) indicate that tau protein pathology and amyloid plaques, which...

Word Count : 14526

Avid Radiopharmaceuticals

Last Update:

plaque, confirming the reliability of the compound in diagnosis. While the tool worked, Pittsburgh compound B relies on the use of carbon-11, a radioactive...

Word Count : 1243

List of PET radiotracers

Last Update:

Desmethoxyfallypride [18F] Mefway [18F] MPPF [18F] Nifene [11C] Pittsburgh compound B [11C] Raclopride [18F] Setoperone [18F] or [11C] N-Methylspiperone...

Word Count : 352

Medical imaging

Last Update:

glucose metabolism, and beta-amyloid plaques using tracers such as Pittsburgh compound B (PiB). Historically less use has been made of quantitative medical...

Word Count : 7148

Methyl trifluoromethanesulfonate

Last Update:

example, [11C]MeOTf has been used extensively in the production of Pittsburgh Compound B, which first allowed β-amyloid plaques to be imaged in a living...

Word Count : 593

Brain positron emission tomography

Last Update:

minophenyl)-6-hydroxybenzothiazole (termed Pittsburgh compound B) developed at the University of Pittsburgh. These amyloid imaging probes permit the visualization...

Word Count : 1867

Dementia

Last Update:

to differentiation by clinical exam. The value of PiB-PET imaging using Pittsburgh compound B (PiB) as a radiotracer has been established in predictive...

Word Count : 22215

Lary Walker

Last Update:

313: 1781-1784; PMID 16990547. "Deficient high-affinity binding of Pittsburgh Compound B in a case of Alzheimer's disease". Rosen RF, Ciliax BJ, Gearing...

Word Count : 1782

Chester Mathis

Last Update:

category of high-efficacy radiopharmaceutical agents, for example Pittsburgh Compound-B (PiB), which can be used to assess beta-amyloid in the living human...

Word Count : 208

Pennsylvania Railroad locomotive classification

Last Update:

D12 D13 D14 D15 - Compound D16 D21 - ex-Vandalia Railroad, built by Baldwin 1871-1873 D22 - ex-Vandalia Railroad, built by Pittsburgh 1883-1889 D23 - ex-Vandalia...

Word Count : 1687

Nellie Bly

Last Update:

and offered her a full-time job. As a writer, Nellie Bly focused her early work for the Pittsburgh Dispatch on the lives of working women, writing a series...

Word Count : 4749

List of Equinox episodes

Last Update:

transduction and biochemical cascades; tests on HL60 did not work; another compound was suberic bishydroxamic acid (SBHA). Narrated by Derek Cooper, directed...

Word Count : 39664

Food Paradise season 4

Last Update:

cast-iron skillet with drawn butter, topped with lump crab meat and chipotle compound butter and served with mashed potatoes and veggies), Cajun Jambalaya, Stuffed...

Word Count : 205

Westinghouse Electric Corporation

Last Update:

in 1999. Westinghouse Electric was founded by George Westinghouse in Pittsburgh, Pennsylvania, on January 8, 1886. Building on the advancement of AC technology...

Word Count : 5219

James Irwin

Last Update:

youngest, of those astronauts to die. Irwin was born March 17, 1930, in Pittsburgh, Pennsylvania, of Scottish, German (maternal side) and Irish descent,...

Word Count : 2820

PDF Search Engine © AllGlobal.net