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Phylogenetic inference using transcriptomic data information


In molecular phylogenetics, relationships among individuals are determined using character traits, such as DNA, RNA or protein, which may be obtained using a variety of sequencing technologies. High-throughput next-generation sequencing has become a popular technique in transcriptomics, which represent a snapshot of gene expression. In eukaryotes, making phylogenetic inferences using RNA is complicated by alternative splicing, which produces multiple transcripts from a single gene. As such, a variety of approaches may be used to improve phylogenetic inference using transcriptomic data obtained from RNA-Seq and processed using computational phylogenetics.

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Phylogenetic inference using transcriptomic data

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may be used to improve phylogenetic inference using transcriptomic data obtained from RNA-Seq and processed using computational phylogenetics. There have...

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Molecular phylogenetics

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may also be used to obtain the transcriptome of an organism, allowing inference of phylogenetic relationships using transcriptomic data. The most common...

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Sequence clustering

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of genomic, "transcriptomic" (ESTs) or protein origin. For proteins, homologous sequences are typically grouped into families. For EST data, clustering...

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Genome skimming

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novel probes that target low-copy genes using transcriptomics via Hyb-Seq. While nuclear genomes assembled using genome skims are extremely fragmented,...

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Multiomics

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They allow insights that cannot be gathered solely from transcriptomic analysis, as RNA data do not contain non-coding genomic regions and information...

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Sequence analysis

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within the context of the hypotheses being investigated. See also: Transcriptomic technologies. Proteome sequence analysis studies the complete set of...

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2023 in science

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T.; Exposito-Alonso, David; et al. (13 October 2023). "Comparative transcriptomics reveals human-specific cortical features". Science. 382 (6667): eade9516...

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De novo gene birth

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testes, and several additional de novo genes were identified using transcriptomic data derived from the testes and male accessory glands of D. yakuba...

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Circulating tumor DNA

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(thanks to phylogenetic evolution and molecular chronology), chromosomal instability, contribution of ctDNA to metastasis through global transcriptomic patterns...

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Evidence of common descent

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performed either using the sequences of a few very ancient proteins or by using ribosomal RNA sequence.[citation needed] Phylogenetic relationships extend...

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German Network for Bioinformatics Infrastructure

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(Research group Walter) Topic: Human Bioinformatics, e.g. Exome, Genomics, Transcriptomics, Metagenomics, Phenotyping, Bioimaging, Epigenetics and Cloud Computing...

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Scallop

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fast and slow muscles in scallops revealed through proteomics and transcriptomics". BMC Genomics. 19 (1): 377. doi:10.1186/s12864-018-4770-2. PMC 5963113...

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Eukaryote hybrid genome

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Pritchard JK, Stephens M, Donnelly P (June 2000). "Inference of population structure using multilocus genotype data". Genetics. 155 (2): 945–59. doi:10.1093/genetics/155...

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Amphibian

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Uno, Yoshinobu (2021). "Inference of evolution of vertebrate genomes and chromosomes from genomic and cytogenetic analyses using amphibians". Chromosome...

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Tetrapod

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"The Making of Calibration Sausage Exemplified by Recalibrating the Transcriptomic Timetree of Jawed Vertebrates". Frontiers in Genetics. 12. 521693. doi:10...

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Barbara Engelhardt

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sequencing, with a particular focus on spatial transcriptomics.  She also has work on Bayesian experimental design using contextual multi-armed bandits, and has...

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MicrobesOnline

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comparative genomic tools for comparing microbial species at the genomic, transcriptomic and functional levels. MicrobesOnline was developed by the Virtual Institute...

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