315 to 317 °C (599 to 603 °F; 588 to 590 K) (decomposition)
Solubility in water
Miscible
Acidity (pKa)
3.39[3]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Nverify (what is YN ?)
Infobox references
Chemical compound
Phthalazine, also called benzo-orthodiazine or benzopyridazine, is a heterocyclic organic compound with the molecular formula C8H6N2. It is isomeric with other naphthyridines including quinoxaline, cinnoline and quinazoline.
^Merck Index, 11th Edition, 7344.
^Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 212. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
^Brown, H.C., et al., in Baude, E.A. and Nachod, F.C., Determination of Organic Structures by Physical Methods, Academic Press, New York, 1955.
Phthalazine, also called benzo-orthodiazine or benzopyridazine, is a heterocyclic organic compound with the molecular formula C8H6N2. It is isomeric with...
C8H6N2. It is isomeric with other naphthyridines including quinoxaline, phthalazine and quinazoline. The free base can be obtained as an oil by treatment...
ring. It is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. It is a colorless oil that melts just above room temperature...
1 Reubi FC (January 1950). "Renal hyperemia induced in man by a new phthalazine derivative". Proceedings of the Society for Experimental Biology and...
Azelastine, sold under the brand name Optivar among others, is a H1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis...
diazanaphthalenes of the benzodiazine subgroup: cinnoline, quinoxaline, and phthalazine. Over 200 biologically active quinazoline and quinoline alkaloids are...
(molar mass: 130.15 g/mol) may refer to: Cinnoline 1,8-Naphthyridine Phthalazine, also called benzo-orthodiazine or benzopyridazine Quinazoline Quinoxaline...
Luminol (C8H7N3O2) is a chemical that exhibits chemiluminescence, with a blue glow, when mixed with an appropriate oxidizing agent. Luminol is a white-to-pale-yellow...
of pyridine), emerald-green; and 1,4-phthalazinedione (a quinone of phthalazine) a green crystalline solid (both soluble in acetone and stable at -77 °C)...
Olaparib, sold under the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults. It is a...
D. (May 20, 2022). "Surprising Chemistry of 6-Azidotetrazolo[5,1- a ]phthalazine: What a Purported Natural Product Reveals about the Polymorphism of Explosives"...
with both N atoms in one ring: cinnoline, quinazoline, quinoxaline, and phthalazine six naphthyridines with one N atom in each ring Desmond J. Brown, Jonathan...
Dihydralazine Cadralazine Endralazine Chemically, the latter two aren't phthalazines; but they are classified as such in the World Health Organization's Anatomical...
Dihydralazine is a prescription drug with antihypertensive properties. It functions by combating the effects of adrenaline, and by expanding the blood...
Cunninghamella elegans can transform the nitrogen containing compound phthalazine It is also able to oxidize the organosulfur compound dibenzothiophene...
Talastine (trade name Ahanon) is an antihistamine. The amide proton from 4-Benzylphalazone is abstracted with KOH, which is then alkylated with dimethylaminoethyl...
Budralazine (INN) is a vasodilator. Akashi A, Chiba T, Suzuki I, Hashimoto H (September 1978). "Pharmacology of budralazine, a new antihypertensive drug"...
piperidine from 1-amino- 5-chloropentane. He was the first to prepare phthalazine in 1893 and, with his student James Colman, pyrimidine in 1899. In 1900...