Global InformationPhage P22 tailspike protein information
| Bifunctional tail protein | |
|---|---|
 PDB rendering based on 2XC1.[1] | |
| Identifiers | |
| Organism | |
| Symbol | 9 |
| Entrez | 1262799 |
| PDB | 2XC1 |
| RefSeq (mRNA) | NC_002371.2 |
| RefSeq (Prot) | NP_059644.1 |
| Other data | |
| EC number | 3.2.1.- |
| Chromosome | Genome: 0.02 - 0.02 Mb |
The tailspike protein (P22TSP) of Enterobacteria phage P22 mediates the recognition and adhesion between the bacteriophage and the surface of Salmonella enterica cells. It is anchored within the viral coat and recognizes the O-antigen portion of the lipopolysaccharide (LPS) on the outer-membrane of Gram-negative bacteria. It possesses endoglycanase activity, serving to shorten the length of the O-antigen during infection.[2]
- ^ 2XC1, 2VFM, 2VKY, 2VFP, 2VFQ, 2VFO, 2VFN, 2VNL, 3TH0, 1TYU, 1TYV, 1TYX, 1TYW, 1TSP, 1CLW, 1QRB, 1QRC, 1QQ1, 1QA1, 1QA2, 1QA3, 1LKT
- ^ Andres D, Baxa U, Hanke C, Seckler R, Barbirz S (Oct 2010). "Carbohydrate binding of Salmonella phage P22 tailspike protein and its role during host cell infection". Biochemical Society Transactions. 38 (5): 1386–1389. doi:10.1042/BST0381386. PMID 20863318.