A peripheral nerve interface is the bridge between the peripheral nervous system and a computer interface which serves as a bi‐directional information transducer recording and sending signals between the human body and a machine processor. Interfaces to the nervous system usually take the form of electrodes for stimulation and recording, though chemical stimulation and sensing are possible.[1] Research in this area is focused on developing peripheral nerve interfaces for the restoration of function following disease or injury to minimize associated losses. Peripheral nerve interfaces also enable electrical stimulation and recording of the peripheral nervous system to study the form and function of the peripheral nervous system. For example, recent animal studies have demonstrated high accuracy in tracking physiological meaningful measures, like joint angle.[2][3] Many researchers also focus in the area of neuroprosthesis, linking the human nervous system to bionics in order to mimic natural sensorimotor control and function.[4] Successful implantation of peripheral nerve interfaces depend on a number of factors which include appropriate indication, perioperative testing, differentiated planning, and functional training.[5] Typically microelectrode devices are implanted adjacent to, around or within the nerve trunk to establish contact with the peripheral nervous system. Different approaches may be used depending on the type of signal desired and attainable.
^Grill WM, Norman SE, Bellamkonda RV (2009). "Implanted neural interfaces: biochallenges and engineered solutions". Annual Review of Biomedical Engineering. 11: 1–24. doi:10.1146/annurev-bioeng-061008-124927. PMID 19400710. S2CID 9380584.
^Koh RG, Balas M, Nachman AI, Zariffa J (January 2020). "Selective peripheral nerve recordings from nerve cuff electrodes using convolutional neural networks". Journal of Neural Engineering. 17 (1): 016042. Bibcode:2020JNEng..17a6042K. doi:10.1088/1741-2552/ab4ac4. PMID 31581142. S2CID 203661866.
^Donaldson PE (May 1983). "The Cooper cable: an implantable multiconductor cable for neurological prostheses". Medical & Biological Engineering & Computing. 21 (3): 371–4. doi:10.1007/BF02478508. PMID 6876913. S2CID 11803616.
^Navarro X, Krueger TB, Lago N, Micera S, Stieglitz T, Dario P (September 2005). "A critical review of interfaces with the peripheral nervous system for the control of neuroprostheses and hybrid bionic systems". Journal of the Peripheral Nervous System. 10 (3): 229–58. doi:10.1111/j.1085-9489.2005.10303.x. PMID 16221284. S2CID 923522.
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disease, including a gait restoration system for paraplegics, a peripheralnerveinterface for amputees, among others. DiLorenzo is the inventor of novel...
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