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Peptide transporter carbon starvation family information


The Peptide Transporter Carbon Starvation (CstA) Family (TC# 2.A.114) is a member of the APC superfamily and consists of proteins from bacteria and archaea. These proteins are of various sizes and topologies. For example, CstA of E. coli has 701 aas with 18 putative TMSs. It has a long N-terminal CstA domain and a short C-terminal DUF4161 domain. This protein is encoded by a carbon starvation inducible gene, cstA, that is under cyclic AMP-CRP control. Circumstantial evidence suggested that it may be a peptide transporter.[1] A Campylobacter jejuni homologue has been shown to transport di- and tripeptides (see TC# 2.A.114.1.5).[2][3] Proteins currently known to belong to the CstA family are listed in the Transporter Classification Database. As of early 2016, there is no crystal structural data available for members of the CstA family on RCSB.

  1. ^ Schultz, JE; Matin, A (March 5, 1991). "Molecular and functional characterization of a carbon starvation gene of Escherichia coli". Journal of Molecular Biology. 218 (1): 129–40. doi:10.1016/0022-2836(91)90879-b. PMID 1848300.
  2. ^ Rasmussen, J. J.; Vegge, C. S.; Frøkiær, H.; Howlett, R. M.; Krogfelt, K. A.; Kelly, D. J.; Ingmer, H. (2013-08-01). "Campylobacter jejuni carbon starvation protein A (CstA) is involved in peptide utilization, motility and agglutination, and has a role in stimulation of dendritic cells". Journal of Medical Microbiology. 62 (Pt 8): 1135–1143. doi:10.1099/jmm.0.059345-0. ISSN 1473-5644. PMID 23682166.
  3. ^ Saier, MH Jr. "2.A.114 The Peptide Transporter Carbon Starvation CstA (CstA) Family". Transporter Classification Database. Saier Lab Bioinformatics Group @ UCSD / SDSC.

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Peptide transporter carbon starvation family

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The Peptide Transporter Carbon Starvation (CstA) Family (TC# 2.A.114) is a member of the APC superfamily and consists of proteins from bacteria and archaea...

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CSTA

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protein Czech and Slovak Transatlantic Award Peptide Transporter Carbon Starvation Family, a family of transporter proteins This disambiguation page lists...

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Transporter Classification Database

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Transporter (NicO) Family 2.A.114 The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family 2.A.115 The Novobiocin Exporter (NbcE) Family...

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APC superfamily

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(KUP) Family 2.A.114 - The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family 2.A.120 - The Putative Amino Acid Permease (PAAP) Family There...

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proteins such as non-ribosomal peptide synthetase, nucleoside hydrolase, TetR family transcriptional regulator, carbon starvation protein A, error-prone DNA...

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membrane protein families. The largest family includes known and putative adhesins. The other four families are porins, iron transporters, flagellum-associated...

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been shown to interact with Cathepsin B and CTSL1. Peptide Transporter Carbon Starvation (cstA) Family GRCh38: Ensembl release 89: ENSG00000121552 – Ensembl...

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epibiont with a larger surface area to grow. Under starvation conditions Under conditions of starvation, the TM7x cells remain vital and multiply. However...

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reaction have been unsuccessful. This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name...

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form. Glucose starvation is a likely common environmental stress encountered by C. albicans in its natural habitat. Glucose starvation causes an increase...

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Lahiri A, Ghosh D, Chatterjee J, Chakravortty D, 2015, Peptide utilizing carbon starvation gene yjiY is required for flagella mediated infection caused...

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