CT scan of non-functioning pancreatic NET before and 6 months after successful treatment with four cycles of 177Lu-DOTATATE.
Specialty
oncology
[edit on Wikidata]
Peptide receptor radionuclide therapy (PRRT) is a type of radionuclide therapy, using a radiopharmaceutical that targets peptide receptors to deliver localised treatment, typically for neuroendocrine tumours (NETs).[1]
^Zaknun, John J.; Bodei, L.; Mueller-Brand, J.; Pavel, M. E.; Baum, R. P.; Hörsch, D.; O’Dorisio, M. S.; O’Dorisiol, T. M.; Howe, J. R.; Cremonesi, M.; Kwekkeboom, D. J. (7 February 2013). "The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours". European Journal of Nuclear Medicine and Molecular Imaging. 40 (5): 800–816. doi:10.1007/s00259-012-2330-6. PMC 3622744. PMID 23389427.
and 24 Related for: Peptide receptor radionuclide therapy information
Peptidereceptorradionuclidetherapy (PRRT) is a type of radionuclidetherapy, using a radiopharmaceutical that targets peptidereceptors to deliver localised...
(PDNECs). Peptidereceptorradionuclidetherapy (PRRT) is a type of radioisotope therapy (RIT) in which a peptide or hormone conjugated to a radionuclide or...
van Essen M, Teunissen JJ, Krenning EP (March 2010). "Peptidereceptorradionuclidetherapy in patients with gastroenteropancreatic neuroendocrine tumors"...
on somatostatin receptor imaging such as octreotide scan.[further explanation needed] Typically, peptidereceptorradionuclidetherapy (PRRT) is considered...
various radionuclides, is used in the treatment and diagnosis of certain types of cancer. When used therapeutically it is an example of peptidereceptor radionuclide...
somatostatin receptor agonists, and to act as radiopharmaceutical therapeutic compound, more specifically to conduct peptideradionuclidereceptortherapy. There...
somatostatin receptor agonists, and to act as radiopharmaceutical therapeutic compound, more specifically to conduct peptideradionuclidereceptortherapy. Some...
metastatic disease, peptidereceptorradionuclidetherapy (PRRT) can be highly effective. This treatment involves attaching a radionuclide (Lutetium-177 or...
with diagnostic capabilities. Radiotheranostics, including PeptideReceptorRadionuclideTherapy (PRRT), hold promise for targeted radiotherapy, enabling...
lutetium-177 and yttrium-90 to treat neuroendocrine tumors (peptidereceptorradionuclidetherapy). Another example is the injection of radioactive yttrium-90...
E, Nistér M (March 2006). "Planning for intracavitary anti-EGFR radionuclidetherapy of gliomas. Literature review and data on EGFR expression". Journal...
a variety of therapeutic radionuclides, such as yttrium-90 or lutetium-177, to enable peptidereceptorradionuclidetherapy (PRRT) for the treatment of...
"Initial Experience With Gallium-68 DOTA-Octreotate PET/CT and PeptideReceptorRadionuclideTherapy for Pediatric Patients With Refractory Metastatic Neuroblastoma"...
Administration. Lutathera is most notable as the first FDA approved peptidereceptorradionuclidetherapy (PRRT) to combat GEP-NETs. GEP-NETs are rare groups of cancer...
carcinoma by targeting cancer-promoting cholecystokinin receptors. PeptideReceptorRadionuclideTherapy (PRRT) A radioactively labeled analogue of minigastrin...
implications for treatment decisions and outcome pertaining to peptidereceptorradionuclidetherapy in patients with advanced neuroendocrine tumour: developing...
β-emitters include Lu-177, Y-90, and I-131. Lutathera is a peptidereceptor radioligand/radionuclidetherapy (approved by the FDA in 2018) specifically for patients...
Abbeele, Annick D. (2018-08-03). "Guidance on 177Lu-DOTATATE PeptideReceptorRadionuclideTherapy from the Experience of a Single Nuclear Medicine Division"...
Zealand. Sarfati was also involved in the establishment of PeptideReceptorRadionuclideTherapy in New Zealand. She also sat on Health New Zealand's Planned...
B-cell malignancies. Targeted therapy can also involve small peptides as "homing devices" which can bind to cell surface receptors or affected extracellular...
cardiotoxicity, leukopenia and nausea. For estrogen-receptor-positive metastatic breast carcinoma the first line of therapy is often tamoxifen or another anti-estrogen...
metoclopramide is used in small-bowel follow-through, small-bowel enema, and radionuclide gastric-emptying studies to reduce the time taken for barium to go through...