2 cross sections of the human brain, with the globus pallidus in green.
Specialty
Neurosurgery
ICD-9-CM
01.42
MeSH
D053860
[edit on Wikidata]
Pallidotomy is a neurosurgical procedure. It is used to treat Parkinson's disease and some other conditions, often as an alternative to deep brain stimulation. It involves placing a tiny electrical probe in the globus pallidus, one of the basal ganglia of the brain, to damage it. Unilateral pallidotomy can cause side effects including problems with language learning, visuospatial constructional ability, and executive functions. Bilateral pallidotomy is not effective, with many severe side effects.
Pallidotomy is a neurosurgical procedure. It is used to treat Parkinson's disease and some other conditions, often as an alternative to deep brain stimulation...
in which damage is deliberately induced, as in a procedure known as a pallidotomy, in which a lesion is created to reduce involuntary muscle tremors. When...
territory of the GPi. This process is called pallidotomy. It is believed that the success of pallidotomies in reducing the effects of movement disorders...
the use of MRI. It is sometimes regarded as a better alternative to pallidotomy or thalamotomy because it is non-permanent. For optimal installation...
can be seen in surgeries used to treat Parkinson's disease, such as Pallidotomy or Thalamotomy (lesioning procedures), or Deep Brain Stimulation (DBS)...
axons DBS represents an advance on previous treatments which involved pallidotomy (i.e., surgical ablation of the globus pallidus) or thalamotomy (i.e...
be more effective and less detrimental in treatment. Posteroventral pallidotomy (PVP) is a specific kind of DBS that destroys a small part of the globus...
invaluable and that they led to improved surgical treatments such as pallidotomy, new drug treatments such as levodopa, and later deep brain stimulation...
Horsley and Robert H. Clarke and in 1951 performed the first stereotactic pallidotomy on an athetoid child. The next year he performed a procaine oil blocking...
PMID 22135580. Gross RE (April 2008). "What happened to posteroventral pallidotomy for Parkinson's disease and dystonia?". Neurotherapeutics. 5 (2): 281–93...
very active in the operation theatre. He performed a large number of pallidotomies, and later also thalamotomies, in Parkinson's disease and capsulotomies...
Unilateral pallidotomy improves tremor and dyskinesia on one side of the body (opposite the side of the brain surgery), but bilateral pallidotomy was found...
functional and stereotactic neurology. With DeLong, he began exploring pallidotomy, using radiofrequency lesioning to destroy cells in the internal segment...
Alternative treatment options include non-pharmacological therapy. Surgery (pallidotomy, thalamotomy) is often viewed as the last viable option. Around 80% of...
without damaging function, for deep brain stimulation placement, or for pallidotomy. Awake craniotomy has increased the scope of tumors that are considered...
the Subthalamic Nucleus in Patients with Parkinson Disease with Prior Pallidotomy or Thalamotomy". Brain Sciences. 8 (4): 66. doi:10.3390/brainsci8040066...
so intractable that he underwent experimental brain surgery, chemical pallidotomy (obliteration of the globus pallidus by injection of alcohol). The intervention...