Effect of spatial atomic arrangement on properties of compounds
Ortho effect is an organic chemistry phenomenon where the presence of an chemical group at the at ortho position or the 1 and 2 position of a phenyl ring, relative to the carboxylic compound changes the chemical properties of the compound. This is caused by steric effects and bonding interactions along with polar effects caused by the various substituents which are in a given molecule, resulting in changes in its chemical and physical properties. The ortho effect is associated with substituted benzene compounds.
There are three main ortho effects in substituted benzene compounds:
Steric hindrance forces cause substitution of a chemical group in the ortho position of benzoic acids become stronger acids.
Steric Inhibition of Protonation caused by substitution of anilines to become weaker bases, compared to substitution of isomers in the meta and para position.
Electrophilic aromatic substitution of disubstituted benzene compounds causes steric effects which determines the regioselectivity of an incoming electrophile in disubstituted benzene compounds
Orthoeffect is an organic chemistry phenomenon where the presence of an chemical group at the at ortho position or the 1 and 2 position of a phenyl ring...
the +M effect) and dominate over that of inductive effect. Hence the result is that they are EDGs and ortho/para directors. Phenol is an ortho/para director...
aromatic carboxylic acids, electron-withdrawing groups substituted at the ortho and para positions can enhance the acid strength. Since the carboxyl group...
Orthokeratology, also referred to as Night lenses, Ortho-K, OK, Overnight Vision Correction, Corneal Refractive Therapy (CRT), Accelerated Orthokeretology...
containing more than 75% orthohydrogen by heating. A mixture or 50:50 mixture of ortho- and parahydrogen can be made in the laboratory by passing it over an iron(III)...
especially the all-ortho isomer, is the causative agent in a number of acute poisonings. Its chronic toxicity is also of concern. The ortho-isomer is rarely...
sexual desires.[medical citation needed] Additional side effect information is provided in the Ortho Evra label information and the Evra Summary of Product...
molecular weight ortho-phthalates and other plasticisers, especially in Europe. Antiplasticizers are polymer additives that have effect opposite to those...
substitution at the ortho or para positions, whereas other groups favor substitution at the meta position. These groups are called either ortho–para directing...
brain development is disputed. At low amounts, it has a mild analgesic effect. According to the International Agency for Research on Cancer, "nicotine...
27, 2018). "Here's Why 'Grey's Anatomy' Fans Will Either Love Or Hate "Ortho God"". Bustle. "Chris Carmack Engaged to Erin Slaver". PEOPLE.com. March...
it is addressed. The word orthopnea uses combining forms of ortho- + -pnea, from Greek ortho, straight, regular, + pnoia, breath. See pronunciation information...
CH3CO2Ag + H2 → 2 Ag + 2 CH3CO2H Silver acetate is a reagent for direct ortho-arylation (to install two adjacent substituents on an aromatic ring) of...
abstracts a proton from the alcohol. The process then repeats at either the ortho or para position (depending on substituents) to give the final diene. The...
meta-tyrosine (also known as 3-hydroxyphenylalanine, L-m-tyrosine, and m-tyr) and ortho-tyrosine (o-tyr or 2-hydroxyphenylalanine), that occur in nature. The m-tyr...
and metal ions and the accompanying enthalpy changes. Part I: Aromatic ortho-hydroxycarboxylic acids (Technical Report)" (PDF). Pure Appl. Chem. 69 (2):...
Trade Commission against OrthoClear Inc. In the end an agreement was made between Align and OrthoClear in which Align paid OrthoClear $20 million for its...
equimolecular quantities of aniline and ortho- and para-toluidines; and aniline oil for safranine, which contains aniline and ortho-toluidine and is obtained from...
synthesis, directed ortho metalation is widely used for the functionalization of arene rings via C-H activation. One main effect that metallic atom substitution...
Nor-QD, others) and in combination with EE (Norinyl, Ortho-Novum, others) or mestranol (Norinyl, Ortho-Novum, others), while NETA is available only in combination...
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