In mass spectrometry, Orbitrap is an ion trap mass analyzer consisting of an outer barrel-like electrode and a coaxial inner spindle-like electrode that traps ions in an orbital motion around the spindle.[1][2] The image current from the trapped ions is detected and converted to a mass spectrum by first using the Fourier transform of time domain of the harmonic to create a frequency signal which is converted to mass.
^Makarov A (March 2000). "Electrostatic axially harmonic orbital trapping: a high-performance technique of mass analysis". Analytical Chemistry. 72 (6): 1156–1162. doi:10.1021/ac991131p. PMID 10740853.
^Hu Q, Noll RJ, Li H, Makarov A, Hardman M, Graham Cooks R (April 2005). "The Orbitrap: a new mass spectrometer". Journal of Mass Spectrometry. 40 (4): 430–443. Bibcode:2005JMSp...40..430H. doi:10.1002/jms.856. PMID 15838939.
In mass spectrometry, Orbitrap is an ion trap mass analyzer consisting of an outer barrel-like electrode and a coaxial inner spindle-like electrode that...
for single analyzer tandem mass spectrometry (e.g. product ion scans). Orbitrap instruments are similar to Fourier-transform ion cyclotron resonance mass...
effective—and therefore most common—on quadrupole mass spectrometers, Orbitrap, and Fourier transform ion cyclotron resonance mass spectrometers. Selected...
(Fourier-transform ion cyclotron resonance), Paul trap or the Kingdon trap. The Orbitrap, introduced in 2005, is based on the Kingdon trap. Other types of mass...
cross lapping of the m/z peaks. If a high-resolution instrument like an orbitrap or an ion cyclotron resonance is used, these two molecules can be distinguished...
to study the proteome. Some important mass spectrometry methods include Orbitrap Mass Spectrometry, MALDI (Matrix Assisted Laser Desorption/Ionization)...
higher-energy collisional dissociation (HCD). HCD is a CID technique specific to orbitrap mass spectrometers in which fragmentation takes place external to the ion...
transform ion cyclotron resonance or Orbitrap mass spectrometer is marketed by Thermo Scientific as the LTQ FT and LTQ Orbitrap, respectively. Glish, G.; McLuckey...
(January 2019). "Oxytocin analysis from human serum, urine, and saliva by orbitrap liquid chromatography-mass spectrometry". Drug Testing and Analysis. 11...
electronics the intensity is typically measured in volts. In FTICR and Orbitraps the frequency domain signal (the y-axis) is related to the power (~amplitude...
extraction coupled with ultra-performance liquid chromatography/Tandem orbitrap mass spectrometry". Rapid Communications in Mass Spectrometry. 32 (20):...
Anti-Diabetic Properties and Identification of Active Compounds Using UHPLC-ESI-Orbitrap-MS/MS in Mangifera odorata L. Peel and Seed Kernel". Molecules. 24 (2):...
J. (2021). "Benzylisoquinoline alkaloid analysis using high-resolution Orbitrap LC-MSn." J Mass Spectrom 56 (2): e4683 Bronwen Jean Bryant and Kathleen...
limitation.[citation needed] Most recently, ion trap techniques such as orbitrap mass spectrometry are also applied to metabolomics research. Nuclear magnetic...
linear quadrupole trap to store ions formed by ESI for injection into an orbitrap mass analyzer. Ions passed through an orifice and skimmer, a quadrupole...
2018. "Award Abstract #0747990 CAREER: A Dual Reaction Cell, ETD-enabled Orbitrap Mass Spectrometer for Top-down Proteomics". National Science Foundation...
of grape volatile composition using secondary electrospray ionization orbitrap mass spectrometry: A preliminary study of grape ripening". Food Control...
reflecting telescope and night vision telescope Alexander Makarov, inventor of orbitrap Dmitry Maksutov, inventor of the Maksutov telescope Boris Mamyrin, inventor...
were awarded with Nobel Prize in Physics for this discovery in 2010. 2005 Orbitrap by Aleksandr Makarov 2006 PEARL (PEtawatt pARametric Laser) First petawatt...
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