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Open fracture information


An open fracture, also called a compound fracture, is a type of bone fracture (broken bone) that has an open wound in the skin near the fractured bone. The skin wound is usually caused by the bone breaking through the surface of the skin. An open fracture can be life threatening or limb-threatening (person may be at risk of losing a limb) due to the risk of a deep infection and/or bleeding. Open fractures are often caused by high energy trauma such as road traffic accidents and are associated with a high degree of damage to the bone and nearby soft tissue.[1] Other potential complications include nerve damage or impaired bone healing, including malunion or nonunion. The severity of open fractures can vary. For diagnosing and classifying open fractures, Gustilo-Anderson open fracture classification is the most commonly used method.[2] This classification system can also be used to guide treatment, and to predict clinical outcomes. Advanced trauma life support is the first line of action in dealing with open fractures and to rule out other life-threatening condition in cases of trauma. The person is also administered antibiotics for at least 24 hours to reduce the risk of an infection.[1]

Diagram of an open, transverse, midshaft radius fracture

Cephalosporins, sometimes with aminoglycosides, are generally the first line of antibiotics and are used usually for at least three days.[3] Therapeutic irrigation, wound debridement, early wound closure and bone fixation core principles in management of open fractures.[4] All these actions aimed to reduce the risk of infections and promote bone healing. The bone that is most commonly injured is the tibia and working-age young men are the group of people who are at highest risk of an open fracture. Older people with osteoporosis and soft-tissue problems are also at risk.

  1. ^ a b Chan, James K.-K.; Aquilina, Alexander L.; Lewis, Sharon R.; Rodrigues, Jeremy N.; Griffin, Xavier L.; Nanchahal, Jagdeep (April 1, 2022). "Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs". The Cochrane Database of Systematic Reviews. 2022 (4): CD013555. doi:10.1002/14651858.CD013555.pub2. ISSN 1469-493X. PMC 8973274. PMID 35363374.
  2. ^ Gustilo, Ramon B. (July 1, 1979). "Use of Antimicrobials in the Management of Open Fractures". Archives of Surgery. 114 (7): 805–808. doi:10.1001/archsurg.1979.01370310047010. ISSN 0004-0010. PMID 454175.
  3. ^ Chan, James K-K; Aquilina, Alexander L; Lewis, Sharon R; Rodrigues, Jeremy N; Griffin, Xavier L; Nanchahal, Jagdeep (April 1, 2022). Cochrane Bone, Joint and Muscle Trauma Group (ed.). "Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs". Cochrane Database of Systematic Reviews. 2022 (4): CD013555. doi:10.1002/14651858.CD013555.pub2. PMC 8973274. PMID 35363374.
  4. ^ Eccles, Simon; Handley, Bob; Khan, Umraz, eds. (2020). Standards for the management of open fractures. Oxford New York, NY: Oxford University Press. ISBN 978-0-19-884936-0.

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