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Sitafloxacin information


Sitafloxacin
Clinical data
Routes of
administration
Oral
ATC code
  • J01MA21 (WHO)
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
CAS Number
  • 127254-12-0 ☒N
PubChem CID
  • 461399
ChemSpider
  • 405945 checkY
UNII
  • 3GJC60U4Q8
KEGG
  • D02475 ☒N
ChEMBL
  • ChEMBL108821 checkY
CompTox Dashboard (EPA)
  • DTXSID5048847 Edit this at Wikidata
Chemical and physical data
FormulaC19H18ClF2N3O3
Molar mass409.82 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • F[C@H]5C[C@H]5N2/C=C(/C(=O)O)C(=O)c1cc(F)c(c(Cl)c12)N4C[C@@H](N)C3(CC3)C4
InChI
  • InChI=1S/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1 checkY
  • Key:PNUZDKCDAWUEGK-CYZMBNFOSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic[1] that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.[citation needed]

  1. ^ Anderson DL (July 2008). "Sitafloxacin hydrate for bacterial infections". Drugs of Today. 44 (7): 489–501. doi:10.1358/dot.2008.44.7.1219561. PMID 18806900.

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