Global InformationObestatin information
| ghrelin/obestatin preprohormone | |||||||
|---|---|---|---|---|---|---|---|
 Obestatin NMR structure in SDS / DPC micellar solution.[1] | |||||||
| Identifiers | |||||||
| Symbol | GHRL | ||||||
| NCBI gene | 51738 | ||||||
| HGNC | 18129 | ||||||
| OMIM | 605353 | ||||||
| RefSeq | NM_016362 | ||||||
| UniProt | Q9UBU3 | ||||||
| Other data | |||||||
| Locus | Chr. 3 p26-p25 | ||||||
| |||||||
Obestatin is a hormone that is produced in specialized epithelial cells of the stomach and small intestine of several animals including humans.[2] Obestatin was originally identified as an anorectic peptide, but its effect on food intake remains controversial.[3]
- ^ PDB: 2JSH; Scrima M, Campiglia P, Esposito C, Gomez-Monterrey I, Novellino E, D'Ursi AM (November 2007). "Obestatin conformational features: a strategy to unveil obestatin's biological role?". Biochem. Biophys. Res. Commun. 363 (3): 500–5. doi:10.1016/j.bbrc.2007.08.200. PMID 17904104.
- ^ Gourcerol G, St-Pierre DH, Taché Y (June 2007). "Lack of obestatin effects on food intake: should obestatin be renamed ghrelin-associated peptide (GAP)?". Regul. Pept. 141 (1–3): 1–7. doi:10.1016/j.regpep.2006.12.023. PMID 17321609. S2CID 45148053.
- ^ Hassouna R, Zizzari P, Tolle V (July 2010). "The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake". J. Neuroendocrinol. 22 (7): 793–804. doi:10.1111/j.1365-2826.2010.02019.x. PMID 20456603. S2CID 43518257.