Schematic diagram of the three-dimensional structure of notexin(PDB: 1AE7).
Identifiers
Organism
Notechis scutatus
Symbol
N/A
CAS number
37223-96-4
PDB
1AE7
UniProt
P00608
Search for
Structures
Swiss-model
Domains
InterPro
Notexin is a toxin produced by the tiger snake (Notechis scutatus). It is a myotoxic and presynaptic, neurotoxic phospholipase A2 (PLA2s).[1] These are enzymes that hydrolyze the bond between a fatty acid tail and glycerol in fatty acids on the 2-position.[2]
^Bersten AD, Handy J (2018-08-15). Oh's Intensive Care Manual E-Book. Elsevier Health Sciences. ISBN 978-0-7020-7606-0.
^Koltai T, Reshkin SJ, Baltazar F, Fliegel L (2021-01-01). "Chapter 5 - Lipid metabolism part II: sphingolipids and ceramides". In Koltai T, Reshkin SJ, Baltazar F, Fliegel L (eds.). Prostate Cancer Metabolism. Academic Press. pp. 137–174. doi:10.1016/B978-0-323-90528-2.00012-6. ISBN 978-0-323-90528-2. S2CID 237968682. Retrieved 2022-03-15.
Notexin is a toxin produced by the tiger snake (Notechis scutatus). It is a myotoxic and presynaptic, neurotoxic phospholipase A2 (PLA2s). These are enzymes...
α subunit yields the PLA2 potency, which is similar to the potency of notexin. Even so, the full potential of the raw toxin is only reached by the combination...
anti-venoms. After one hour of inoculation of these toxins, including notexin and taipoxin, many of the affected nerve terminals show signs of irreversible...
Mollier P, Brochier G, Morot Gaudry-Talarmain Y (1990). "The action of notexin from tiger snake venom (Notechis scutatus scutatus) on acetylcholine release...
antigenically related to Micrurus nigrocinctus nigroxin, Notechis scutatus notexin, mulgotoxin of Pseudechis australis and textilotoxin of Pseudonaja textilis...
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