1961 scientific experiment instrumental in deciphering the genetic code
Nirenberg (right) and Matthaei at the National Institutes of Health
The Nirenberg and Matthaei experiment was a scientific experiment performed in May 1961 by Marshall W. Nirenberg and his post-doctoral fellow, J. Heinrich Matthaei, at the National Institutes of Health (NIH). The experiment deciphered the first of the 64 triplet codons in the genetic code by using nucleic acid homopolymers to translate specific amino acids.
In the experiment, an extract was prepared from bacterial cells that could make protein without the presence of intact living cells. An artificial form of RNA consisting entirely of uracil-containing nucleotides (polyuridylic acid or poly-U) was added to the extract, causing it to form a protein composed entirely of the amino acid phenylalanine. This experiment cracked the first codon of the genetic code and showed that RNA controlled the production of specific types of protein.
and 11 Related for: Nirenberg and Matthaei experiment information
The NirenbergandMatthaeiexperiment was a scientific experiment performed in May 1961 by Marshall W. Nirenbergand his post-doctoral fellow, J. Heinrich...
The Nirenbergand Leder experiment was a scientific experiment performed in 1964 by Marshall W. Nirenbergand Philip Leder. The experiment elucidated the...
deciphering the codons of the genetic code and the first demonstration of messenger RNA (see NirenbergandMatthaeiexperiment). In August 1961, at the International...
Brenner et al. experiment using frameshift mutations to support the triplet nature of the genetic code (1961). NirenbergandMatthaeiexperiment demonstrating...
Championship season. The NirenbergandMatthaeiexperiment was performed by Heinrich Matthaei. The Poly-U-Experiment enabled recognition and understanding of...
Leslie Barnett and R.J. Watts-Tobin prove the triplet nature of the genetic code. 1961 – Marshall W. Nirenbergand J. Heinrich Matthaei deciphered the...
Ultimately the code was broken in the 1961 NirenbergandMatthaeiexperiment, which did not use computers and which was not carried out by RNA Tie Club...
Barnett and Watts-Tobin experiment first demonstrated that codons consist of three DNA bases. Marshall Nirenbergand J. Heinrich Matthaei were the first...
synthesis of nucleic acids played a part in helping Marshall Nirenbergand Heinrick Matthaei to decipher the genetic code. They studied polynucleotide phosphorylase...
Heinrich Matthaeiand Marshall Nirenberg (1962), Mertelsmann began his research for his medical doctorate as a medical student in Heinrich Matthaei's Laboratory...
economist and won the prize for economics in 2020 Marshall Nirenberg (Ph.D. 1957), Chief of Biomedical Genetics, National Heart, Lung and Blood Institute...