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Nerve agent information


Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter. Nerve agents are irreversible acetylcholinesterase inhibitors used as poison.

Poisoning by a nerve agent leads to constriction of pupils, profuse salivation, convulsions, and involuntary urination and defecation, with the first symptoms appearing in seconds after exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to the loss of the body's control over respiratory and other muscles. Some nerve agents are readily vaporized or aerosolized, and the primary portal of entry into the body is the respiratory system. Nerve agents can also be absorbed through the skin, requiring that those likely to be subjected to such agents wear a full body suit in addition to a respirator.

Nerve agents are generally colorless and tasteless liquids. Nerve agents evaporate at varying rates depending on the substance. None are gases in normal environments. The popular term "nerve gas" is inaccurate.[1]

Agents Sarin and VX are odorless; Tabun has a slightly fruity odor and Soman has a slight camphor odor.[2]

  1. ^ Kaszeta, Dan (2020). Toxic: A history of nerve agents from Nazi Germany to Putin's Russia. London: C. Hurst & Co. p. 263. ISBN 9781787383067.
  2. ^ "Medical Management Guidelines (MMGs): Nerve Agents (GA, GB, GD, VX)". Agency for Toxic Substances and Disease Registry (ATSDR). U.S. Department of Health and Human Services. Archived from the original on 25 January 2018. Retrieved 8 March 2018.

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