Neonatal lupuserythematosus is an autoimmune disease in an infant born to a mother with anti-Ro/SSA and with or without anti-La/SSB antibodies.[1][2] The disease most commonly presents with a rash resembling subacute cutaneous lupus erythematosus and can have systemic abnormalities such as complete heart block or hepatosplenomegaly.[3] Neonatal lupus is usually benign and self-limited.[3] Many of the clinical manifestations are transient, but certain heart problems can be permanent.[4] Diagnosis is based on maternal antibodies and clinical manifestations.[1] Treatment and management is mainly supportive and focused on preventing complete heart block if possible.[5]
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subacute cutaneous lupuserythematosus and can have systemic abnormalities such as complete heart block or hepatosplenomegaly. Neonatallupus is usually benign...
PMID 15934442. S2CID 8871456. Nitta, Y. (1997). "Lupuserythematosus profundus associated with neonatallupuserythematosus". British Journal of Dermatology. 136...
resembling discoid lupuserythematosus, and sometimes with systemic abnormalities such as heart block or hepatosplenomegaly. Neonatallupus is usually benign...
abnormalities and is associated with autoimmune conditions such as systemic lupuserythematosus, Hashimoto's thyroiditis, and thymoma. Lambert–Eaton myasthenic syndrome...
conditions. For example: Lupuserythematosus overlap syndrome. Lesions of this syndrome share features of both lupuserythematosus and lichen planus. Lesions...
Infection late in gestation or immediately following birth is referred to as "neonatal varicella". Maternal infection is associated with premature delivery. The...
the individual's own proteins. Many autoimmune diseases (notably lupuserythematosus) are associated with such antibodies. Antibodies are produced by...
Methylprednisolone is used to treat several rheumatic diseases, such as Systemic LupusErythematosus (SLE) and Rheumatoid Arthritis (RA). Methylprednisolone dosage and...
infection are complications in severe cases and can be fatal if present in the neonatal period. Fewer than 100 cases of CMTC have been published worldwide. Petrozzi...
birth, and neonatal teeth are teeth that emerge through the gingiva during the first month of life (the neonatal period). The incidence of neonatal teeth varies...
was found during three liver biopsies of individuals with systemic lupuserythematosus and autoimmune liver disease. The autoimmune reaction was found to...
perinatal infection, the primary manifestation is infection of the eye (neonatal conjunctivitis or ophthalmia neonatorum) when the newborn is exposed to...
melanosis, ochronosis (endogenous and exogenous), and cutaneous erythematosuslupus. Additionally, it should not be confused with phytophotodermatosis...
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