The Negativicutes are a class of bacteria in the phylum Bacillota, whose members have a peculiar cell wall with a lipopolysaccharide outer membrane which stains gram-negative, unlike most other members of the Bacillota.[1] Although several neighbouring Clostridia species (firmicute bacteria) also stain gram-negative, the proteins responsible for the unusual diderm structure of the Negativicutes may have actually been laterally acquired from Pseudomonadota (formerly Proteobacteria).[1][2][3][4] Additional research is required to confirm the origin of the diderm cell envelope in the Negativicutes.
Most members of this class are obligate anaerobes, and occur in habitats such as rivers, lakes, and the intestines of vertebrates. They range from spherical forms, such as Megasphaera and Veillonella, to curved rods, as typified by the selenomonads. Selenomonas has a characteristic crescent shape, with flagella inserted on the concave side, while Sporomusa is similar, but nonmotile. Their names refer to this distinctive morphology: selene means moon, and musa means banana.[5]
^ abSutcliffe IC (2010). "A phylum level perspective on bacterial cell envelope architecture". Trends Microbiol. 18 (10): 464–470. doi:10.1016/j.tim.2010.06.005. PMID 20637628.
^Gupta RS (2011). "Origin of diderm (Gram-negative) bacteria: antibiotic selection pressure rather than endosymbiosis likely led to the evolution of bacterial cells with two membranes". Antonie van Leeuwenhoek. 100 (2): 171–182. doi:10.1007/s10482-011-9616-8. PMC 3133647. PMID 21717204.
^Campbell C, Sutcliffe IC, Gupta RS (2014). "Comparative proteome analysis of Acidaminococcus intestini supports a relationship between outer membrane biogenesis in Negativicutes and Proteobacteria" (PDF). Arch Microbiol. 196 (4): 307–310. doi:10.1007/s00203-014-0964-4. PMID 24535491. S2CID 253722630.
^Tocheva EI, Matson EG, Morris DM, Moussavi F, Leadbetter JR, Jensen GJ (2011). "Peptidoglycan remodeling and conversion of an inner membrane into an outer membrane during sporulation". Cell. 146 (5): 799–812. doi:10.1016/j.cell.2011.07.029. PMC 3176627. PMID 21884938.
^Marchandin, H.; Teyssier, C.; Campos, J.; Jean-Pierre, H.; Roger, F.; Gay, B.; Carlier, J. -P.; Jumas-Bilak, E. (2009). "Negativicoccus succinicivorans gen. nov., sp. nov., isolated from human clinical samples, emended description of the family Veillonellaceae and description of Negativicutes classis nov., Selenomonadales ord. nov. and Acidaminococcaceae fam. nov. in the bacterial phylum Firmicutes". International Journal of Systematic and Evolutionary Microbiology. 60 (6): 1271–1279. doi:10.1099/ijs.0.013102-0. PMID 19667386.
of members within the Negativicutes, as well as the distribution of molecular signatures, supports the view that the Negativicutes are in fact an independent...
Megasphaera is a genus of Bacillota bacteria classified within the class Negativicutes. This classification has been reexamined. It appears that this genus...
followed by two phyla: Bacillota (except for the classes Mollicutes and Negativicutes) and the Actinomycetota. In contrast, members of the Chloroflexota (green...
the sole energy source for growth. Like other members of the class Negativicutes, they are gram-negative, despite being Bacillota, which are normally...
Dialister is a genus of Bacillota bacteria classified within the class Negativicutes. The currently accepted taxonomy[as of?] is based on the List of Prokaryotic...
Dialister is a genus of Firmicutes bacteria classified within the class Negativicutes. Dialister pneumosintes has been difficult to identify and culture....
Erysipelotrichia Ludwig et al. 2010 Limnochordia Watanabe et al. 2015 Negativicutes Marchandin et al. 2010 Thermolithobacteria Sokolova et al. 2007 Synonyms...
the class Negativicutes. See the List of Prokaryotic names with Standing in Nomenclature. Data extracted from J.P. Euzéby. "Negativicutes". Retrieved...
intestini supports a relationship between outer membrane biogenesis in Negativicutes and Proteobacteria" (PDF). Arch Microbiol. 196 (4): 307–310. Bibcode:2014ArMic...
Pectinatus is a genus of Bacillota bacteria classified within the class Negativicutes. The currently accepted taxonomy is based on the List of Prokaryotic...
Propionispora is a genus of Bacillota bacteria classified within the class Negativicutes. List of bacterial orders List of bacteria genera J.P. Euzéby. "Propionispora"...
"Genome-based taxonomic framework for the class Negativicutes: division of the class Negativicutes into the orders Selenomonadales emend., Acidaminococcales...
Pelosinus is a genus of Bacillota bacteria classified within the class Negativicutes. The currently accepted taxonomy is based on the List of Prokaryotic...
emended description of the family Veillonellaceae and description of Negativicutes classis nov., Selenomonadales ord. nov. and Acidaminococcaceae fam....
is a genus in the phylum Bacillota (Bacteria). Members of the class Negativicutes, stain gram negative, despite being firmicutes The name Dendrosporobacter...
order Eubacteriales to the new order Selenomonadales in the new class Negativicutes. Despite most of the members of the Bacillota staining positive for...
raffinosivorans and Propionispira arboris, by comparing them to a new strain of Negativicutes, WK011T, as well as the original type species, Zymophilus paucivorans...
Megamonas is a genus of Bacillota bacteria classified within the class Negativicutes. The currently accepted taxonomy is based on the List of Prokaryotic...
Sporomusa is a genus of Bacillota bacteria classified within the class Negativicutes. Further examination of members of this clade suggest that this group...
intestini supports a relationship between outer membrane biogenesis in Negativicutes and Proteobacteria" (PDF). Arch. Microbiol. 196 (4): 307–310. doi:10...
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