dentate gyrus of hippocampal formation granule cell
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
protein kinase activity
nucleotide binding
G protein-coupled peptide receptor activity
hormone binding
guanylate cyclase activity
GTP binding
lyase activity
natriuretic peptide receptor activity
phosphorus-oxygen lyase activity
ATP binding
peptide hormone binding
adenylate cyclase activity
protein kinase binding
peptide receptor activity
Cellular component
integral component of membrane
membrane
plasma membrane
receptor complex
guanylate cyclase complex, soluble
intracellular anatomical structure
Biological process
negative regulation of smooth muscle cell proliferation
regulation of cardiac conduction
intracellular signal transduction
positive regulation of renal sodium excretion
positive regulation of urine volume
body fluid secretion
cyclic nucleotide biosynthetic process
receptor guanylyl cyclase signaling pathway
regulation of blood pressure
cGMP biosynthetic process
protein phosphorylation
cell surface receptor signaling pathway
regulation of vascular permeability
dopamine metabolic process
negative regulation of cell growth
negative regulation of angiogenesis
G protein-coupled receptor signaling pathway
blood vessel diameter maintenance
positive regulation of cGMP-mediated signaling
cGMP-mediated signaling
signal transduction
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4881
18160
Ensembl
ENSG00000169418
ENSMUSG00000027931
UniProt
P16066
P18293
RefSeq (mRNA)
NM_000906
NM_008727
RefSeq (protein)
NP_000897
NP_032753
Location (UCSC)
Chr 1: 153.68 – 153.69 Mb
Chr 3: 90.36 – 90.37 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR1 gene.
^ abcGRCh38: Ensembl release 89: ENSG00000169418 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000027931 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
receptor A), also known as NPR1, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR1 gene. NPR1 is a membrane-bound guanylate...
recognized by nonexpresser of PR genes 1 (NPR1) due to redox change in the cytosol, resulting in the reduction of NPR1. NPR1, which usually exists in a multiplex...
modification of host NON-EXPRESSOR OF PATHOGENESIS RELATED 1 (NPR1) during the course of infection. NPR1 is an important regulator of salicylic acid (SA) and jasmonic...
to five years in a new bed, at a different site. The NPR1 gene from Arabidopsis thaliana, AtNPR1, confers A. thaliana's broad-spectrum resistance when...
XXB 750 is an experimental injected drug that targets natriuretic peptide (NPR1) and is developed to treat resistant hypertension. It was also tried for...
the addition of a transgene, the Arabidopsis defense master regulator gene NPR1. This quickly produces a large number of changes because of the conservation...
Productivity Review. 19 (3): 1–6. doi:10.1002/1520-6734(200022)19:3<1::AID-NPR1>3.0.CO;2-9. Ziewitz, M. (2019). "Rethinking gaming: The ethical work of optimization...
and other pathogens. In Zea mays, salicylic acid and JA are mediated by NPR1 (nonexpressor of pathogenesis-related genes1), which is essential in preventing...
early work involved the identification of key components in SAR, including NPR1. More recently, the Lab made discoveries which provided new insights into...
cyclase-A (GC-A) also known as natriuretic peptide receptor-A (NPRA/ANPA) or NPR1 guanylyl cyclase-B (GC-B) also known as natriuretic peptide receptor-B (NPRB/ANPB)...
relief). TRPV1 has been shown to interact with: CALM1 SNAPAP SYT9 CBD AEA NPR1 PKG The dorsal root ganglion (DRG) neurons of mammals were known to express...
dependent genes and the defense regulatory gene, non expressor of PR genes (NPR1). Transgenerational SAR in the progeny was associated with increased acetylation...
defense signaling cascades throughout the plant. For example, the SAR NPR1 (AtNPR1) gene is of special importance and acts to suppress the infection faculties...
induced as part of systemic acquired resistance. Expression is mediated by the NPR1 gene and the salicylic acid pathway, both involved in resistance to fungal...
downstream kinase Npr1 in response to amino acid flux, hindering its activity. When TORC1 becomes inactive in response to low amino acids, Npr1 becomes an active...
there is proven association with the TAOK2 gene and its interaction with the NPR1-SEMA3A signaling pathway. Research shows growth of basal dendrites when more...
peptide precursor A (NPPA) in oviduct and of natriuretic peptide receptor 1 (NPR1) in spermatozoon are involved in mouse sperm chemotaxis and fertilization...
Global Information
