NOSIP information

NOSIP
Identifiers
Aliases	NOSIP, CGI-25, nitric oxide synthase interacting protein
External IDs	OMIM: 616759 MGI: 1913644 HomoloGene: 9315 GeneCards: NOSIP
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,590,262 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,727,634 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; triceps brachii muscle; ; blood; ; gastrocnemius muscle; ; sperm; ; vastus lateralis muscle; ; lymph node; ; spleen; ; canal of the cervix; ; amniotic fluid;
	Top expressed in
	spermatid; ; spermatocyte; ; interventricular septum; ; lip; ; blastocyst; ; internal carotid artery; ; morula; ; yolk sac; ; external carotid artery; ; seminiferous tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; transferase activity; RNA binding; ubiquitin protein ligase activity;
Cellular component	cytoplasm; cytosol; Golgi membrane; nucleus;
Biological process	negative regulation of catalytic activity; negative regulation of nitric-oxide synthase activity; multicellular organism development; protein ubiquitination; regulation of nitric-oxide synthase activity;
	Sources:Amigo / QuickGO
Orthologs
	51070
	66394
	ENSG00000142546
	ENSMUSG00000003421
	Q9Y314
	Q9D6T0
	NM_001270960; NM_015953; NM_001363649
	NM_001163684; NM_025533
	NP_001257889; NP_057037; NP_001350578
	NP_001157156; NP_079809
	Wikidata
View/Edit Human	View/Edit Mouse

Nitric oxide synthase-interacting protein is an enzyme that in humans is encoded by the NOSIP gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000142546 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003421 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Dedio J, Konig P, Wohlfart P, Schroeder C, Kummer W, Muller-Esterl W (Jan 2001). "NOSIP, a novel modulator of endothelial nitric oxide synthase activity". FASEB J. 15 (1): 79–89. doi:10.1096/fj.00-0078com. PMID 11149895. S2CID 34485514.
^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
^ "Entrez Gene: NOSIP nitric oxide synthase interacting protein".

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