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Murid gammaherpesvirus 68 information


Murid gammaherpesvirus 68
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Orthoherpesviridae
Genus: Rhadinovirus
Species:
Murid gammaherpesvirus 4
Virus:
Murid gammaherpesvirus 68

Murid gammaherpesvirus 68 (MuHV-68) is an isolate of the virus species Murid gammaherpesvirus 4, a member of the genus Rhadinovirus. It is a member of the subfamily Gammaherpesvirinae in the family of Herpesviridae. MuHV-68 serves as a model for study of human gammaherpesviruses which cause significant human disease including B-cell lymphoma and Kaposi's sarcoma. The WUMS strain of MuHV-68 was fully sequenced and annotated in 1997,[1] and the necessity of most of its genes in viral replication was characterized by random transposon mutagenesis.[2]

  1. ^ Herbet W. Virgin IV; Philip Latreille; Pamela Wamsley; Kymberlie Hallsworth; Karen E. Weck; Albert J. Dal Canto & Samuel H. Speck (August 1997). "Complete sequence and genomic analysis of murine gammaherpesvirus 68". Journal of Virology. 71 (8): 5894–904. doi:10.1128/JVI.71.8.5894-5904.1997. PMC 191845. PMID 9223479.
  2. ^ Moon Jung Song; Seungmin Hwang; Wendy H. Wong; Ting-Ting Wu; Sangmi Lee; Hsiang-I Liao & Ren Sun (March 2005). "Identification of viral genes essential for replication of murine γ-herpesvirus 68 using signature-tagged mutagenesis". Proceedings of the National Academy of Sciences of the United States of America. 102 (10): 3805–10. Bibcode:2005PNAS..102.3805S. doi:10.1073/pnas.0404521102. PMC 553290. PMID 15738413.

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