For the journal, see Mucosal Immunology (journal).
Components of mucosal immune system
Mucosal immunology is the study of immune system responses that occur at mucosal membranes of the intestines, the urogenital tract, and the respiratory system.[1] The mucous membranes are in constant contact with microorganisms, food, and inhaled antigens.[2] In healthy states, the mucosal immune system protects the organism against infectious pathogens and maintains a tolerance towards non-harmful commensal microbes and benign environmental substances.[1] Disruption of this balance between tolerance and deprivation of pathogens can lead to pathological conditions such as food allergies, irritable bowel syndrome, susceptibility to infections, and more.[2]
The mucosal immune system consists of a cellular component, humoral immunity, and defense mechanisms that prevent the invasion of microorganisms and harmful foreign substances into the body. These defense mechanisms can be divided into physical barriers (epithelial lining, mucus, cilia function, intestinal peristalsis, etc.) and chemical factors (pH, antimicrobial peptides, etc.).[3]
^ ab"Mucosal immunology - Latest research and news". Nature Portfolio. Springer Nature Limited. Retrieved 2016-11-08.
^ abZheng D, Liwinski T, Elinav E (June 2020). "Interaction between microbiota and immunity in health and disease". Cell Research. 30 (6): 492–506. doi:10.1038/s41422-020-0332-7. PMC 7264227. PMID 32433595.
^Brandtzaeg P (2009). Brandtzaeg P, Isolauri E, Prescott SL (eds.). "'ABC' of mucosal immunology". Nestle Nutrition Workshop Series. Paediatric Programme. Nestlé Nutrition Institute Workshop Series. 64: 23–38, discussion 38–43, 251–7. doi:10.1159/000235781. ISBN 978-3-8055-9167-6. PMID 19710513.
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Mucosalimmunology is the study of immune system responses that occur at mucosal membranes of the intestines, the urogenital tract, and the respiratory...
IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity". MucosalImmunology. 2 (1): 74–84. doi:10.1038/mi.2008.68. PMID 19079336. Bonner...
cells are generated in mucosal immune responses and contribute to the bone marrow plasma cell pool in mice". MucosalImmunology. 9 (1): 83–97. doi:10.1038/mi...
of the mucosal immune system in the female reproductive tract. Lang TJ (December 2004). "Estrogen as an immunomodulator". Clinical Immunology. 113 (3):...
The intestinal mucosal barrier, also referred to as intestinal barrier, refers to the property of the intestinal mucosa that ensures adequate containment...
School Celiac Research Program. In addition, he is director of the MucosalImmunology and Biology Research Center at MGHfC, where he oversees a research...
"Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut". MucosalImmunology. 4 (6): 603–611. doi:10.1038/mi.2011.41. PMC 3774538...
"The role of lipoxin A4 in endometrial biology and endometriosis". MucosalImmunology. 6 (3): 439–50. doi:10.1038/mi.2013.9. PMC 4062302. PMID 23485944...
lymphocytes (IEL) are lymphocytes found in the epithelial layer of mammalian mucosal linings, such as the gastrointestinal (GI) tract and reproductive tract...
immunologist, and vaccinologist, known for his research on cholera and mucosalimmunology, specifically, for his leadership in developing "the world's first...
He served Society for MucosalImmunology as Treasurer from 2007 to 2011, as a member of the editorial board of MucosalImmunology from 2008, as associate...
Russell RW (2011). "Structure and function relationships in IgA". MucosalImmunology. 4 (6): 590–597. doi:10.1038/mi.2011.39. PMID 21937984. Damelang T...
Hungarian-born Canadian doctor. He is considered one of the fathers of mucosalimmunology. Born in Budapest, of Jewish parents, he escaped to England in 1939...
Cheroutre, Hilde; Lambrecht, Bart N.; Kelsall, Brian L. (15 April 2015). MucosalImmunology. ISBN 9780124158474. Kedl, Ross M.; Hsieh, Elena W. Y.; Morrison,...
Molecular Immunology in Cincinnati Children's Hospital Medical Center before returning to NIAID in 2005 as Head of the MucosalImmunology Unit in the...
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