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Methylmalonic acid semialdehyde information


Methylmalonic acid semialdehyde
Names
Preferred IUPAC name
2-Methyl-3-oxopropanoic acid
Other names
Methylmalonate semialdehyde, 2-methyl-3-oxopropanoic acid
Identifiers
CAS Number
  • 6236-08-4 ☒N
3D model (JSmol)
  • Interactive image
  • Interactive image
ChEBI
  • CHEBI:16256 checkY
ChemSpider
  • 290 checkY
KEGG
  • C00349 checkY
PubChem CID
  • 296
UNII
  • 036CTC7X1V ☒N
CompTox Dashboard (EPA)
  • DTXSID60274265 Edit this at Wikidata
InChI
  • InChI=1S/C4H6O3/c1-3(2-5)4(6)7/h2-3H,1H3,(H,6,7) checkY
    Key: VOKUMXABRRXHAR-UHFFFAOYSA-N checkY
  • InChI=1/C4H6O3/c1-3(2-5)4(6)7/h2-3H,1H3,(H,6,7)
    Key: VOKUMXABRRXHAR-UHFFFAOYAB
SMILES
  • CC(C=O)C(=O)O
  • O=CC(C(=O)O)C
Properties
Chemical formula
C4H6O3
Molar mass 102.09 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Methylmalonic acid semialdehyde is an intermediate in the metabolism of thymine and valine.[1]

  1. ^ Voet, Donald (2011). Biochemistry. Judith G. Voet (4th ed.). Hoboken, NJ: John Wiley & Sons. ISBN 978-0-470-57095-1. OCLC 690489261.

and 13 Related for: Methylmalonic acid semialdehyde information

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Methylmalonic acid semialdehyde

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Methylmalonic acid semialdehyde is an intermediate in the metabolism of thymine and valine. Methylmalonate-semialdehyde dehydrogenase (acylating) Voet...

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Methylmalonic acidemias

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buildup of a toxic level of methylmalonic acid in body liquids and tissues. Due to the disturbed branched-chain amino acids (BCAA) metabolism, they are...

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Formiminoglutamic acid

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decreased methylmalonic acid, increased folate and a decrease in homocysteine. Formiminotransferase cyclodeaminase Glutamate-1-semialdehyde Glutamic acid...

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Semialdehyde

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In organic chemistry, a semialdehyde is a compound containing an aldehyde and a carboxylic acid functional groups. Semialdehydes are common in biochemistry...

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Threonine

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and microorganisms, threonine is synthesized from aspartic acid via α-aspartyl-semialdehyde and homoserine. Homoserine undergoes O-phosphorylation; this...

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List of carboxylic acids

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Carboxylic acids are organic acids characterized by a carboxyl (-COOH) functional group. The naming of these compounds is governed by IUPAC nomenclature...

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Valine

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metabolic diseases: Combined malonic and methylmalonic aciduria (CMAMMA) Maple syrup urine disease (MSUD) Methylmalonic acidemia Propionic acidemia Lower levels...

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Methionine

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aspartic acid, while the sulfur may come from cysteine, methanethiol, or hydrogen sulfide. First, aspartic acid is converted via β-aspartyl semialdehyde into...

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Isoleucine

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ketogenic) or fatty acids. The degradation of isoleucine is impaired in the following metabolic diseases: Combined malonic and methylmalonic aciduria (CMAMMA)...

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Homocysteine

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where it is accompanied by decreased methylmalonic acid, increased folate, and a decrease in formiminoglutamic acid. This is the opposite of MTHFR C677T...

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Chromosome 4

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list, see the link in the infobox on the right. AASDH: aminoadipate-semialdehyde dehydrogenase ACVR1: activin-like kinase 2 (ALK-2) ACOX3: encoding enzyme...

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Sepiapterin reductase deficiency

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delayed by an earlier diagnosis of an initially unclassified form of methylmalonic aciduria at the age of 2. At that time the hypotonia and delayed development...

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List of OMIM disorder codes

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CD320 Methylmalonic aciduria, cblD type, variant 2; 277410; C2orf25 Methylmalonic aciduria, vitamin B12-responsive; 251100; MMAA Methylmalonic aciduria...

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