structure of MerF. It has two trans-membrane helices. PDB 2h3o.[1]
Identifiers
Symbol
MerF
Pfam
PF11431
InterPro
IPR021091
TCDB
1.A.72
OPM superfamily
218
OPM protein
2lj2
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
The mercury transporter superfamily (TC# 1.A.72) is a family of transmembrane bacterial transporters of mercury ions. The common origin of all Mer superfamily members has been established.[2] The common elements between family members are included in TMSs 1-2. A representative list of the subfamilies and proteins that belong to those subfamilies is available in the Transporter Classification Database.
^De Angelis, A. A.; Howell, S. C.; Nevzorov, A. A.; Opella, S. J. (2006). "Structure Determination of a Membrane Protein with Two Trans-membrane Helices in Aligned Phospholipid Bicelles by Solid-State NMR Spectroscopy". Journal of the American Chemical Society. 128 (37): 12256–12267. doi:10.1021/ja063640w. PMC 3236029. PMID 16967977.
^Mok, Timothy; Chen, Jonathan S.; Shlykov, Maksim A.; Jr, Milton H. Saier (2012-06-02). "Bioinformatic Analyses of Bacterial Mercury Ion (Hg2+) Transporters". Water, Air, & Soil Pollution. 223 (7): 4443–4457. Bibcode:2012WASP..223.4443M. doi:10.1007/s11270-012-1208-3. ISSN 0049-6979. S2CID 83571260.
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