Global InformationMengovirus information
| Mengovirus | |
|---|---|
| |
| Surface depiction of Mengovirus (2MEV) coloured by radial height to illuminate surface features | |
Virus classification 
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| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Picornavirales |
| Family: | Picornaviridae |
| Genus: | Cardiovirus |
| Species: | Cardiovirus A
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| Virus: | Mengovirus
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Mengovirus, also known as Columbia SK virus, mouse Elberfield virus, and Encephalomyocarditis virus (EMCV), belongs to the genus Cardiovirus which is a member of the Picornaviridae.[1] Its genome is a single stranded positive-sense RNA molecule, making the Mengoviruses a class IV virus under the Baltimore classification system. The genome is approximately 8400nt in length, and has 5’ VG protein (Virus genome protein) and a 3’ polyadenine tail. Mengovirus was isolated by George W. A. Dick in 1948, in the Mengo district of Entebbe in Uganda, from a captive rhesus monkey that had developed hind limb paralysis.[2][3]
- ^ Carocci, M; Bakkali-Kassimi, L (2012). "The encephalomyocarditis virus". Virulence. 3 (4): 351–67. doi:10.4161/viru.20573. PMC 3478238. PMID 22722247.
- ^ Dick, G. W.; Smithburn, K. C.; Haddow, A. J. (948). "Mengo Encephalomyelitis Virus. Isolation and Immunological Properties". Br J Exp Pathol. 29 (6): 547–558. PMC 2073198.
- ^ Dick, G.W.A.; Haddow, A.J.; Best, A.M.; Smithburn, K.C. (1948). "Mengo Encephalomyelitis". The Lancet. 252 (6521): 286–289. doi:10.1016/S0140-6736(48)90652-7.