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Melanoblast information


A melanoblast is a precursor cell of a melanocyte. These cells migrate from the trunk neural crest cells (in terms of axial level from neck to posterior end) dorsolaterally between the ectoderm and dorsal surface of the somites.[1]

  1. ^ Mort, Richard L.; Jackson, Ian J.; Patton, E. Elizabeth (2015-02-15). "The melanocyte lineage in development and disease". Development. 142 (4): 620–632. doi:10.1242/dev.106567. ISSN 0950-1991. PMC 4325379. PMID 25670789.

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Melanoblast

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A melanoblast is a precursor cell of a melanocyte. These cells migrate from the trunk neural crest cells (in terms of axial level from neck to posterior...

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Melanocyte

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stem cells develop into both keratinocyte precursors and melanoblasts - and these melanoblasts supply both hair and skin (moving into the basal layer of...

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Piebald

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Location of the unpigmented spots is dependent on the migration of melanoblasts (primordial pigment cells) from the neural crest to paired bilateral...

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Precursor cell

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precursor cell Myeloblast Thymocyte Meiocyte Megakaryoblast Promegakaryocyte Melanoblast Lymphoblast Bone marrow precursor cells Normoblast Angioblast (endothelial...

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Silkie

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the Silkie fowl correlates with abnormal migration of fate-restricted melanoblasts and loss of environmental barrier molecules". Developmental Dynamics...

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Amelanism

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Melanocyte stem cells are called melanoblasts. Conditions associated with abnormalities in the migration of melanoblasts are known collectively as piebaldism...

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Cat coat genetics

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The deafness is due to a reduction in the population and survival of melanoblast stem cells, which in addition to creating pigment-producing cells, develop...

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Stem cell factor

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pigmentation. In melanogenesis, melanoblasts migrate from the neural crest to their appropriate locations in the epidermis. Melanoblasts express the KIT receptor...

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Freeze brand

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citing Foulks: "melanocytes continually arise from undifferentiated melanoblasts in the dermis during feather growth. Apparently the presence of whitetipped...

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Neurocutaneous melanosis

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is believed to be related to the abnormal postzygotic development of melanoblasts and mutations of the NRAS gene. Neurocutaneous melanosis is associated...

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White horse

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leg depends on the complete migration and clonal proliferation of the melanoblasts in the mesoderm of the developing fetus, thus ensuring that limbs and...

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GPNMB

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McCallion AS, Green ED, Bennett DC, Pavan WJ (February 2009). "Gpnmb is a Melanoblast-Expressed, MITF-Dependent Gene". Pigment Cell & Melanoma Research. 22...

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Owen Sansom

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Finn, AJ; Groben, PA; et al. (2011). "P-Rex1 is required for efficient melanoblast migration and melanoma metastasis". Nature Communications. 2: 555. Bibcode:2011NatCo...

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Dominant white

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leg depends on the complete migration and clonal proliferation of the melanoblasts in the mesoderm of the developing fetus, thus ensuring that limbs and...

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PAX3

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various cell types and structures arising from the neural crest, such as melanoblasts, Schwann cell precursors, and dorsal root ganglia. In addition, Pax3-expressing...

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PREX1

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Campbell AD, et al. (November 2011). "P-Rex1 is required for efficient melanoblast migration and melanoma metastasis". Nature Communications. 2: 555. Bibcode:2011NatCo...

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Paul McMenamin

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Seyed-Razavi Y, Kalirai H, Insall RH, Machesky LM, Coupland SE. (2020) Melanoblasts Populate the Mouse Choroid Earlier in Development Than Previously Described...

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FOXD3

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RA (August 2005). "Candidate functional promoter variant in the FOXD3 melanoblast developmental regulator gene in autosomal dominant vitiligo". The Journal...

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MYO10

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Bhawan J, Coluccio LM (July 2018). "Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis". Scientific Reports...

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