Magnesium orotate, the magnesium salt of orotic acid, is a mineral supplement. It can be used in treating extracellular magnesium deficiency, as well as in mitigating magnesium depletion that inhibits the binding of adenosine triphosphate via orotic acid, which provides binding sites.[1]
^Classen HG (2004). "Magnesium orotate--experimental and clinical evidence". Romanian Journal of Internal Medicine. 42 (3): 491–501. PMID 16366126.
Magnesiumorotate, the magnesium salt of orotic acid, is a mineral supplement. It can be used in treating extracellular magnesium deficiency, as well...
Magnesium hydroxide, suspended in water, is used in milk of magnesia antacids and laxatives. Magnesium chloride, oxide, gluconate, malate, orotate, glycinate...
Schmidbaur H (1990). "Orotate complexes. Synthesis and crystal structure of lithium orotate(—I) monohydrate and magnesium bis[orotate(—I)] octahydrate"....
acid of the stomach, which may not be (and usually is not) complete. Magnesiumorotate may be used as adjuvant therapy in patients on optimal treatment for...
Orotate phosphoribosyltransferase (OPRTase) or orotic acid phosphoribosyltransferase is an enzyme involved in pyrimidine biosynthesis. It catalyzes the...
latter is converted to orotate by dihydroorotate oxidase. The net reaction is: (S)-Dihydroorotate + O2 → Orotate + H2O2 Orotate is covalently linked with...
nervous system in a variety of ways. While the citrate, carbonate, and orotate salts are currently used to treat bipolar disorder, other lithium salts...
Li2CO3, lithium citrate, Li3C6H5O7, lithium sulphate, Li2SO4, and lithium orotate, LiC5H3N2O4·H2O. Lithium is also used in batteries as an anode and its...
catalyzed by orotidylate decarboxylase. The orotidylate is produced from orotate, which is combined with 5-phosphoribosyl-1-pyrophosphate (PRPP) to form...
under ultraviolet light. Pyrimidine biosynthesis creates derivatives —like orotate, thymine, cytosine, and uracil— de novo from carbamoyl phosphate and aspartate...
localized in the mitochondria. UMPS is a bifunctional enzyme consisting of orotate phosphoribosyltransferase (OPRT) and orotidine monophosphate decarboxylase...
tetrahydrofolate. Pyrimidines, on the other hand, are synthesized from the base orotate, which is formed from glutamine and aspartate. All organisms are constantly...
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