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Loose anagen syndrome information


Loose anagen syndrome
Other namesLoose anagen hair syndrome[1]
Hair loss and thinning at the back of the scalp
Pronunciation
  • / lʉːs ænədʒən ‘sɪndrəʊm /
SpecialtyDermatology
Differential diagnosisShort anagen syndrome, alopecia areata, telogen effluvium, trichotillomania, toxic ingestion[2]
TreatmentMinoxidil[3]
Frequency2-2.5 cases per million people, 6:1 ratio; females to males respectively[3][4]

Loose anagen syndrome, also known as loose anagen hair syndrome, is a hair disorder related to dermatology. It is characterised by the easy and pain free detachment of anagen staged hairs from the scalp.[5][6][3] This hair condition can be spontaneous or genetically inherited.[6][7]

Loose anagen syndrome is primarily described in fair-haired children who have easily dislodgeable hair.[8]: 641  It is commonly present in younger children, generally between the ages of 2 and 8.[4] It is especially observed in female children with light coloured hair. Females and males have differences in hair. There are knowledge gaps about loose anagen syndrome in males, and a 6 to 1 incidence ratio of females to males with loose anagen syndrome, respectively.[3][4] Loose anagen syndrome may also be misdiagnosed in males, as males traditionally have short hair.[2]

Patients with loose anagen hair syndrome usually experience hair thinning around the whole scalp or at the occipital scalp, at the back of the head.[7] Although this is a hair condition, there have only been reports of this condition also affecting the patient's eyebrows. There are no noted impacts on any other hairs of the body such as eyebrows and eyelashes.[7] It also does not have any impacts on nails, teeth or skin.[2]

Loose anagen syndrome is more predominantly seen in fairer skin and it is not as common in dark skin populations. Abdel-Raouf, El-Din, Awad, Ashraf, Mohammad, Hosan, Hasan, Moetaz, Tag and Mohammad have reported a population of dark skinned individuals with loose anagen syndrome.[3] Each year there are approximately 2 to 2.5 cases per million people with loose anagen hair syndrome.[4]

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ a b c "Loose Anagen Syndrome (pluckable hair, loose hair syndrome, loose anagen hair syndrome, syndrome of loosely attached hair in childhood)". Dermatology Advisor. 2019-03-13. Retrieved 2020-05-28.
  3. ^ a b c d e Dhurate, R. P., Deshpande, D. J. (2010). "Loose Anagen Hair Syndrome". International Journal of Trichology. 2 (2): 96–100. doi:10.4103/0974-7753.77513. PMC 3107966. PMID 21712911.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ a b c d Leung, A., Barankin, B. (2006). "Why Is This Child's Hair Not Growing". Consultant. 15 (11).{{cite journal}}: CS1 maint: multiple names: authors list (link)
  5. ^ Baden, H., Kvedar, J., Magro, C. (1992). "Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children". Arch Dermatol. 128 (1): 1349–1353. doi:10.1001/archderm.1992.01680200059007. PMID 1417022.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ^ a b Price, V., Gummer, C. (1989). "Loose anagen syndrome". Journal of the American Academy of Dermatology. 20 (2): 249–256. doi:10.1016/S0190-9622(89)70030-X. PMID 2915060.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  7. ^ a b c Maxfield, Luke; Cook, Christopher (2020), "Loose Anagen Syndrome", StatPearls, StatPearls Publishing, PMID 30252286, retrieved 2020-05-28
  8. ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.

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