List of biophysically important macromolecular crystal structures information
Crystal structures of protein and nucleic acid molecules and their complexes are central to the practice of most parts of biophysics, and have shaped much of what we understand scientifically at the atomic-detail level of biology. Their importance is underlined by the United Nations declaring 2014 as the International Year of Crystallography, as the 100th anniversary of Max von Laue's 1914 Nobel prize for discovering the diffraction of X-rays by crystals. This chronological list of biophysically notable protein and nucleic acid structures is loosely based on a review in the Biophysical Journal.[1] The list includes all the first dozen distinct structures, those that broke new ground in subject or method, and those that became model systems for work in future biophysical areas of research.
^Richardson JS, Richardson DC (2014). "Biophysical highlights from 54 years of macromolecular crystallography". Biophysical Journal. 106 (3): 510–525. Bibcode:2014BpJ...106..510R. doi:10.1016/j.bpj.2014.01.001. PMC 3945011. PMID 24507592.
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chronological listofbiophysically notable protein and nucleic acid structures is loosely based on a review in the Biophysical Journal. The list includes...
software for macromolecular crystallography Carlos Bustamante (Peruvian-born American, 1951–) — known for single-molecule biophysicsof molecular motors...
(2003). "Specific Radiation Damage Can Be Used to Solve MacromolecularCrystalStructures". Structure. 11 (2): 217–224. doi:10.1016/S0969-2126(03)00006-6...
the modern IUPAC definition. The modern concept of polymers as covalently bonded macromolecularstructures was proposed in 1920 by Hermann Staudinger, who...
how they acquire the structures they have, and how alterations in their structures affect their function. This subject is of great interest to biologists...
With the development of X-ray crystallography, it became possible to sequence protein structures. The first protein structures to be solved were hemoglobin...
Biochemistry and Biophysics at UC San Francisco, whose research is focussed on understanding the basic principles ofmacromolecularstructure and function...
phenomena of life starting from the macromolecular properties that generate them. Two categories of macromolecules in particular are the focus of the molecular...
that lacks a fixed or ordered three-dimensional structure, typically in the absence of its macromolecular interaction partners, such as other proteins or...
surfaces of plants, the majority of bacteria are bound to surfaces in biofilms. Biofilms are also important in medicine, as these structures are often...
Importantstructuresofmacromolecular complexes were determined in CEF. Examples for important membrane complexes include the atomic structuresof complex...
involves a concentrated beam of X-rays that is directed at a crystal. When X-rays are projected to a crystalstructure, the crystal diffracts the X-rays in...
pioneer of multidimensional macromolecular NMR spectroscopy laying foundations of 3D structure determination of proteins in solution; member of the United...
specimens this aims to stabilize the specimen's mobile macromolecularstructure by chemical crosslinking of proteins with aldehydes such as formaldehyde and...
immediately adjacent to the intercalation site, as evidenced by several crystalstructures. By intercalation, doxorubicin can also induce histone eviction from...
degradation rates and heterogeneous structures. Conversely, synthetic-based polymers have more defined structures, increased stability, and controlled...
replication of evolvable macromolecular systems, and mapping the chemical landscape of potential primordial informational polymers. The advent of polymers that could...