Iodized oil, also known as ethiodized oil, brand name Lipiodol, is a medication derived from poppyseed oil and iodine. When given by injection, it is a radio-opaque contrast agent that is used to outline structures in radiological investigations.[2][3] When given orally or by intramuscular injection once or twice a year, it prevents endemic goitre in remote communities.[4] It has an additional use in gastric variceal obliteration as a dilutant that does not affect polymerization of cyanoacrylate.
When used as tissue contrast, iodized oil has a risk of entering the vein and causing embolism in the brain and lungs.[5] There is a boxed warning referring to the risk of embolism.[6] Use as iodine supplementation is recommended in regions where deficiency is common, otherwise it is not recommended.[4] It should not be used for hysterosalpingography in pregnancy.[6]
Iodized oil was first made in 1901 by Marcel Guerbet and Laurent Lafay. Originally used to treat iodine deficiency, it was identified as an effective radiocontrast in 1921 by Sicard and Forestier, before returning as a tool to treat iodine deficiency in goiter eradication campaigns of the 1980s.[7] Under the name "iodine", iodized oil is on the World Health Organization's List of Essential Medicines, in liquid and capsule form.[4][8]
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 Oct 2023.
^Ahrar K, Gupta S (January 2003). "Hepatic artery embolization for hepatocellular carcinoma: technique, patient selection, and outcomes". Surgical Oncology Clinics of North America. 12 (1): 105–126. doi:10.1016/s1055-3207(02)00089-3. PMID 12735133.
^Sato T (April 2002). "Locoregional immuno(bio)therapy for liver metastases". Seminars in Oncology. 29 (2): 160–167. doi:10.1053/sonc.2002.31716. PMID 11951214.
^ abcWorld Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 499. hdl:10665/44053. ISBN 9789241547659.
^Gomi T, Hasegawa M (2012). "Radiological contrast agents and radiopharmaceuticals". Side Effects of Drugs Annual. 34: 749–760. doi:10.1016/b978-0-444-59499-0.00046-5. ISBN 978-0-444-59499-0.
^Bonnemain B, Guerbet M (1995). "Histoire du Lipiodol (1901-1994) ou Comment un médicament peut évoluer avec son temps" [The history of Lipiodol (1901-1994) or How a medication may evolve with the times]. Revue d'Histoire de la Pharmacie (in French). 42 (305): 159–170. doi:10.3406/pharm.1995.4238. PMID 11640460.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
Iodized oil, also known as ethiodized oil, brand name Lipiodol, is a medication derived from poppyseed oil and iodine. When given by injection, it is a...
contrast materialPages displaying wikidata descriptions as a fallback Lipiodol – Medication derived from poppyseed oil and iodine often used as a contrast...
check the response of the tumor to the procedure. Lipiodol – mixed with chemotherapeutic agents (Lipiodol is nonocclusive, combined with Gelfoam, Ivalon...
in the cervical canal. For the first HSG, Carey used collargol in 1914. Lipiodol was introduced by Sicard and Forestier in 1924, and remained a popular...
1926 by André Guerbet, the son of Marcel Guerbet who in 1901 discovered Lipiodol – the first iodinated X-ray contrast agent. In 2017 Guerbet’s revenues...
a chylothorax. Lymphangiography procedures use the contrast dye agent lipiodol, which is injected into the lymphatic vessels. The chylothorax shows up...
be painted over a layer of poppyseed oil. Poppyseed oil is the basis of lipiodol, a radiocontrast agent used in medical radiology and a treatment for iodine...
Cyanoacrylate, a common component in 'super glue' is often mixed 1:1 with lipiodol to prevent polymerization in the endoscopy delivery optics, and to show...
vasculature also supplies the tumor. Post treatment noncontrast CBCT confirms lipiodol staining of the tumor, which improves operator confidence of complete tumor...
antineoplastic drug (e.g. cisplatin) mixed with a radio-opaque contrast (e.g. Lipiodol) and an embolic agent (e.g. Gelfoam) into the right or left hepatic artery...
ways: Conventional transarterial chemoembolization (cTACE): Injection of lipiodol with high dose chemotherapy with or without microparticles directly into...
its complications, due to Lipiodol retention mainly intratumoral, but also diffusely intrahepatic. On ultrasound, Lipiodol appears intensely hyperechoic...
instructor, Jean-Athanase Sicard (1872–1929), he demonstrated the use of Lipiodol for spinal X-ray examinations. Forestier competed in the 1920 Summer Olympics...
ways: Conventional transarterial chemoembolization (cTACE): Injection of lipiodol with high dose chemotherapy with or without microparticles directly into...
air. In a second step, hook wires, thread needles, or contrast agent (lipiodol, iopamidol) are introduced into or next to the lesion to ensure visibility...
earliest accounts of chest X-ray and contrast, that is bronchography and lipiodol. On Sunday 23 September 1951, the thoracic surgical team from Westminster...
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