This article is about the lamina densa in skin. For other uses, see basal lamina and glomerular basement membrane.
The lamina densa is a component of the basement membrane zone between the epidermis and dermis of the skin, and is an electron-dense zone between the lamina lucida and dermis, synthesized by the basal cells of the epidermis, and composed of (1) type IV collagen, (2) anchoring fibrils made of type VII collagen, and (3) dermal microfibrils.[1]
^James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. Page 5-6. ISBN 0-7216-2921-0.
The laminadensa is a component of the basement membrane zone between the epidermis and dermis of the skin, and is an electron-dense zone between the lamina...
layers: the lamina lucida (electron-lucent), laminadensa (electron-dense), and lamina fibro-reticularis (electron-lucent). The laminadensa was formerly...
that the lamina lucida is an artifact created when preparing the tissue, and that the lamina lucida is therefore equal to the laminadensa in vivo. Basal...
been linked to colitis-associated cancer. Basal lamina (part of which is also known as laminadensa) Myofibroblast Submucosa Burkitt, H. George; Young...
called the lamina lucida, while the denser-colored layer closer to the connective tissue is called the laminadensa. The electron-dense laminadensa layer...
nephritis caused by mutations in type IV collagen, leading to a split laminadensa of the glomerular basement membrane. It also affects the eye and inner...
circulation. The basal lamina is composed of 3 layers: lamina rara externa, laminadensa, and lamina rara interna. The lamina rara externa is adjacent...
cells connecting the basal epithelial cells to the lamina lucida, which is part of the basal lamina. Hemidesmosomes are also involved in signaling pathways...
limb and the afferent arteriole. It contains three components: the macula densa, juxtaglomerular cells, and extraglomerular mesangial cells.: 404 Patients...
covered by a lamina coat which is approximately 50 nm wide. The laminar coat is separable into two layers; the laminadensa and lamina lucida. In between...
the lamina lucida and laminadensa. The lamina lucida appears as a low density clear zone medial to the epithelial basal cells. The laminadensa has a...
internal basal lamina consists of a lamina lucida and laminadensa. This internal basal lamina of the EA is continuous with the external basal lamina between...
including two of the circumventricular organs – the vascular organ of the lamina terminalis, and the subfornical organ. They contribute to osmoregulation...
upper lamina lucida in bullous pemphigoid, the target antigen in MMP is the C-terminus of BP180 which is located in the lower lamina lucida and lamina densa...
electron lucent layer adjacent to the basal plasma membrane and the laminadensa that is a closely packed network of fibers. There are dramatic changes...
of Na+ and Cl- to the macula densa. If a reduced NaCl concentration in the distal tubule is sensed by the macula densa, renin release by juxtaglomerular...
and integrins. Ideally, the basement membrane must contain a lamina lucida and a laminadensa. Stratified squamous epithelium: is simulated by oral keratinocytes...
against the 97 kDa component of BPAG2 (bullous pemphigoid antigen 2) in the lamina lucida are the primary cause of linear IgA bullous dermatosis (LABD). The...
endothelial cells; f) epithelial cells, fibroblasts, and certain cells in the lamina propria of the small and large intestines; g) mast cells; h) HK-2 cells...
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